Spironolactone Impurity 14 CAS 53866-20-9
| CAS No. | 53866-20-9 |
| Molecular Formula | C25H32O5 |
| Molecular Weight | 412.52 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO supplies Spironolactone Impurity 14 (CAS 53866-20-9), a pharmacopoeial impurity reference standard (molecular formula C25H32O5, MW 412.52 g/mol) used for the identification and quantification of trace impurities in APIs.
The molecular framework of Spironolactone Impurity 14 (C25H32O5) is characterized by a flavonoid core, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
As a certified reference material (CRM), Spironolactone Impurity 14 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C25H32O5 |
| Molecular Weight | 412.52 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | >95% |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1972 |
Related Spironolactone Standards
- Spironolactone EP Impurity A (CAS 132458-33-4)
- Spironolactone EP Impurity E (CAS 33784-05-3)
- Spironolactone (CAS 52-01-7)
- Spironolactone D3 (CAS 52-01-7 (Unlabeled))
- Spironolactone EP Impurity I (CAS CATO-C4X-13459)
- Spironolactone-d7(Major) (CAS CATO-CCAD302541)
- Spironolactone Impurity 20 (CAS CATO-C4X-134520)
- Spironolactone EP Impurity G (CAS 880106-10-5)
Recommended Standards
- Canagliflozin Impurity 58 (CAS CATO-C4X-112358)
- Budesonide EP Impurity H (Mixture of Epimer) (CAS 313474-58-7)
- 1,3-Bis(tosyloxy)-2,2-dimethylpropane (CAS 22308-12-9)
- N-Nitroso Venlafaxine EP Impurity H (Mixture of Diastereomers) (CAS CATO-C4X-143453)
- Pretomanid Impurity 15 (CAS 1353753-57-7)
- Ketoprofen Impurity 53 (CAS 1420774-68-0)
- Meclofenoxate Impurity 6 (CAS CATO-C4X-24696)
- N,N-Diethyl-2,6-dimethylpyridin-4-amine (CAS 959247-35-9)
- 2-(tert-Butylamino)ethan-1-ol (CAS 4620-70-6)
- (S)-2-Amino-1-(2-((benzyl(methyl)amino)methyl)pyrrolidin-1-yl)ethanone (CAS 1354016-88-8)
- Binimetinib Impurity 6 (CAS CATO-C4X-30506)
- Docosahexaenoic Acid Ethyl Ester (CAS 81926-94-5)
- 1,3-Dibromo-5-(bromomethyl)-2-chlorobenzene (CAS 1350760-65-4)
- Protein Kinase C (alpha) Peptide (CAS 159939-84-1)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com