Canagliflozin Impurity 58 CAS CATO-C4X-112358
| CAS No. | CATO-C4X-112358 |
| Molecular Formula | C24H25FO3S |
| Molecular Weight | 412.52 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
CATO supplies Canagliflozin Impurity 58 (CAS CATO-C4X-112358), a pharmacopoeial impurity reference standard (molecular formula C24H25FO3S, MW 412.52 g/mol) used for the identification and quantification of trace impurities in APIs.
Canagliflozin Impurity 58 (C24H25FO3S) contains a steroid core, a sulfone group, a hydroxyl group, an ether linkage, fluorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | C24H25FO3S |
| Molecular Weight | 412.52 g/mol |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | F-containing |
| Sulfur Atoms | 1 |
Related Canagliflozin Standards
- Canagliflozin Impurity 36 (CAS CATO-C4X-112336)
- Canagliflozin Impurity 20 (CAS CATO-C4X-112320)
- Canagliflozin Impurity 27 (CAS 898566-17-1)
- Canagliflozin Impurity 51 (CAS 2444540-10-5)
- Canagliflozin Impurity 52 (CAS CATO-C4X-112352)
- Canagliflozin Impurity 53 (CAS CATO-C4X-112353)
- Canagliflozin Impurity 54 (CAS CATO-C4X-112354)
- Canagliflozin Impurity 55 (CAS CATO-C4X-112355)
Recommended Standards
- 1,3-Bis(tosyloxy)-2,2-dimethylpropane (CAS 22308-12-9)
- Spironolactone Impurity 14 (CAS 53866-20-9)
- Quinidine benzoate (CAS 60723-45-7)
- Budesonide EP Impurity H (Mixture of Epimer) (CAS 313474-58-7)
- Atracurium Impurity 116 (CAS CATO-C4X-1850116)
- Mianserin impurity 41 (CAS CATO-C4X-136941)
- Erlotinib Impurity 146 (CAS CATO-C4X-1069146)
- 3-Bromo-2-(pyridin-4-yl)-1H-indole (CAS 343350-55-0)
- 2-Ethyl-5,7-dimethyl-3H-imidazo[4,5-β]pyridine (CAS 133240-06-9)
- 1-(Dimethylamino)cyclopentane-1-carbonitrile (CAS 22912-31-8)
- (6aR,9R)-5a-hydroxy-N-methyl-5-oxo-N-propyl-7-(trideuteriomethyl)-6,6a,8,9-tetrahydro-4H-indolo[4,3-fg]quinoline-9-carboxamide (CAS 1322625-15-9)
- (4-Bromophenyl)(3-fluoro-4-methylphenyl)methanone (CAS 844879-18-1)
- 2-Tert-Butyl-4-Methylphenol (CAS 2409-55-4)
- Semaglutide impurity 47 (CAS CATO-C4X-222647)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com