Doxycycline CAS 564-25-0
| CAS No. | 564-25-0 |
| Molecular Formula | C22H24N2O8 |
| Molecular Weight | 444.43 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Doxycycline is closely related to a flavonoid core, an amide group, a hydroxyl group, an ether linkage in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
Doxycycline (CAS 564-25-0), molecular formula C22H24N2O8 and molecular weight 444.43 g/mol, is a CATO reference standard with documented purity and traceability.
Based on its molecular formula C22H24N2O8, Doxycycline contains a flavonoid core, an amide group, a hydroxyl group, an ether linkage; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 444.43 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures Doxycycline under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C22H24N2O8 |
| Molecular Weight | 444.43 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | >95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Nitrogen Atoms | 2 |
Related Doxycycline Standards
- Doxycycline EP Impurity A (CAS 3219-99-6)
- Doxycycline EP Impurity C (CAS 6543-77-7)
- Doxycycline EP Impurity D (CAS 97583-08-9)
- Doxycycline Impurity 8 (CAS CATO-C4X-19318)
- Doxycycline Impurity 21 (CAS CATO-C4X-193121)
- Doxycycline EP Impurity F (CAS 122861-53-4)
- Doxycycline EP Impurity B (CAS CATO-C4X-19312)
- Doxycycline-d3 (CAS 2747918-45-0)
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- 2-Thioxo-1,2-dihydropyrimidine-4-carboxamide (CAS 155957-51-0)
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Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com