Doxycycline EP Impurity D CAS 97583-08-9

Purity >90%In StockPharmacopoeial Impurity Standards
CAS No.97583-08-9
Molecular FormulaC22H24N2O8
Molecular Weight444.43 g/mol
CategoryPharmacopoeial Impurity Standards / EP Impurities
AvailabilityIn Stock

Chemical Structure

Doxycycline EP Impurity D CAS 97583-08-9 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 444.43 g/mol gives Doxycycline EP Impurity D distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

Doxycycline EP Impurity D (CAS 97583-08-9) is a certified pharmaceutical impurity reference standard with the molecular formula C22H24N2O8 and a molecular weight of 444.43 g/mol.

Structurally, Doxycycline EP Impurity D (C22H24N2O8) contains a flavonoid core, an amide group, a hydroxyl group, an ether linkage. The molecule exhibits a degree of unsaturation (DBE) of 12.0, corresponding to approximately 12 ring(s) or double-bond equivalent(s). With a molecular weight of 444.43 g/mol, it falls into the moderately-high-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.

As a certified reference material (CRM), Doxycycline EP Impurity D meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC22H24N2O8
Molecular Weight444.43 g/mol
AppearancePale yellow to yellow crystalline powder
Purity>90%
StorageStore in a cool place (≤25°C), protect from light, keep sealed and dry
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening
Degree of Unsaturation (DBE)12.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1984
Nitrogen Atoms2

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