Apremilast CAS 608141-41-9
| CAS No. | 608141-41-9 |
| Molecular Formula | C22H24N2O7S |
| Molecular Weight | 460.50 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), Apremilast meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
CATO supplies Apremilast (CAS 608141-41-9), a certified reference material (molecular formula C22H24N2O7S, MW 460.50 g/mol) for analytical method development and quality control.
The molecular framework of Apremilast (C22H24N2O7S) is characterized by a flavonoid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C22H24N2O7S |
| Molecular Weight | 460.50 g/mol |
| Purity | >95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1985 |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related Apremilast Standards
- Apremilast Impurity 1 (CAS 608141-44-2)
- rac-Apremilast (CAS 253168-86-4)
- Apremilast Impurity 130 (CAS 2487573-03-3)
- Apremilast Impurity 4 (CAS 2201974-01-6)
- Apremilast impurity 9 (CAS CATO-C4X-10099)
- Apremilast-D3 (CAS CATO-C4X-1009129)
- Apremilast Impurity 126 (CAS CATO-C4X-1009126)
- Apremilast-d5 (CAS 1258597-47-5)
Recommended Standards
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