Guaifenesin Impurity 1 CAS 61248-75-7
| CAS No. | 61248-75-7 |
| Molecular Formula | C10H14O4 |
| Molecular Weight | 198.22 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Based on its molecular formula C10H14O4, Guaifenesin Impurity 1 contains a carboxylic acid group, a hydroxyl group, an ether linkage, an aromatic ring system; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 198.22 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Guaifenesin Impurity 1 (CAS 61248-75-7) is a high-purity analytical reference standard with the molecular formula C10H14O4 and a molecular weight of 198.22 g/mol.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C10H14O4 |
| Molecular Weight | 198.22 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1974 |
Related Guaifenesin Standards
- Guaifenesin EP Impurity B (CAS 14007-09-1)
- Guaifenesin-d3 (CAS 1189924-85-3)
- Guaifenesin EP Impurity B-D4 (CAS 114609-65-3)
- Guaifenesin-Glyceryl-<SUP>13</SUP>C<SUB>3</SUB> (CAS 1173019-31-2)
- Guaifenesin Metabolite (Glyceryl Guaiacolate Metabolite) (CAS 13057-65-3)
- Guaifenesin Impurity 5 (CAS 2049-21-0)
- Guaifenesin Impurity 7 (CAS 120-80-9)
- Guaifenesin EP Impurity D (CAS 16929-60-5)
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