Nilotinib Impurity 9 CAS 641571-05-3
| CAS No. | 641571-05-3 |
| Molecular Formula | C28H22F3N7O |
| Molecular Weight | 529.52 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies Nilotinib Impurity 9 (CAS 641571-05-3), a pharmacopoeial impurity reference standard (molecular formula C28H22F3N7O, MW 529.52 g/mol) used for the identification and quantification of trace impurities in APIs.
Nilotinib Impurity 9 (C28H22F3N7O) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C28H22F3N7O |
| Molecular Weight | 529.52 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 20.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1985 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 7 |
Related Nilotinib Standards
- Nilotinib Hydrochloride Monohydrate EP Impurity H (CAS 641571-15-5)
- Nilotinib (CAS 641571-10-0)
- Nilotinib Impurity 42 (CAS CATO-C4X-125642)
- Nilotinib-d3 (CAS 1215678-43-5)
- Nilotinib-d6 (CAS 1268356-17-7)
- Nilotinib Impurity 43 (CAS CATO-C4X-125643)
- Nilotinib Hydrochloride Monohydrate EP Impurity F (CAS 2119583-24-1)
- Nilotinib EP Impurity E (CAS 2119583-26-3)
Recommended Standards
- Cefoperazone Impurity N3 (CAS 73240-09-2)
- 1-Cyclopropyl-7-[4-[(2,3-dihydro-1,4-benzodioxin-6-yl)sulfonyl]-1-piperazinyl]-6-fluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid (CAS 743441-94-3)
- Cefoperazone EP Impurity A (CAS 73240-08-1)
- 5-Bromo-3-(2-nitrovinyl)-1H-indole (CAS 25217-77-0)
- Nemonoxacin Impurity 42 (CAS 1027572-10-6)
- Paliperidone Impurity 116 (CAS 1200448-51-6)
- Betamethasone Valerate EP Impurity H (CAS 52619-18-8)
- Furo[3,2-b]pyridin-2-ylboronic acid (CAS 1423787-72-7)
- 2-(Pyridin-2-yl)oxazolidine (CAS 100377-21-7)
- N-(4-Fluorobenzyl)-4-(thiophen-2-yl)tetrahydro-2H-pyran-4-carboxamide (CAS 877650-20-9)
- 2-Fluoro-1-isopropoxy-3-nitrobenzene (CAS 1369873-60-8)
- methyl 4-chloro-1-methyl-1H-pyrrolo[3,2-c]pyridine-7-carboxylate (CAS 871819-43-1)
- N2-Ethylbenzo[1,2-b:4,5-b']difuran-2,6-diamine (CAS 863992-65-8)
- Des-Ala21-Tirzepatide (CAS CATO-CPTD788952)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com