Lifitegrast Impurity 10 CAS 77095-51-3
| CAS No. | 77095-51-3 |
| Molecular Formula | C9H6O3 |
| Molecular Weight | 162.14 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Lifitegrast Impurity 10 (CAS 77095-51-3) is a certified pharmaceutical impurity reference standard with the molecular formula C9H6O3 and a molecular weight of 162.14 g/mol.
Structurally, Lifitegrast Impurity 10 (C9H6O3) contains a carboxylic acid group, a hydroxyl group, an ether linkage, an aromatic ring system. The molecule exhibits a degree of unsaturation (DBE) of 7.0, corresponding to approximately 7 ring(s) or double-bond equivalent(s). With a molecular weight of 162.14 g/mol, it falls into the medium-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
As a certified reference material (CRM), Lifitegrast Impurity 10 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C9H6O3 |
| Molecular Weight | 162.14 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1979 |
Related Lifitegrast Standards
- Lifitegrast Impurity 165 (CAS CATO-C4X-2409165)
- Lifitegrast Impurity 168 (CAS CATO-C4X-2409168)
- Lifitegrast Impurity 42 (CAS 588703-29-1)
- Lifitegrast Impurity N60 (CAS 933752-32-0)
- Lifitegrast Impurity 19 (CAS 1289646-90-7)
- Lifitegrast Impurity N68 (CAS 89315-56-0)
- Lifitegrast Impurity 108 (CAS CATO-C4X-2409108)
- Lifitegrast Impurity 109 (CAS CATO-C4X-2409109)
Recommended Standards
- 1,6-Anhydro-β-D-glucofuranose (CAS 7425-74-3)
- Ascorbic Acid Impurity 39 (CAS 492-30-8)
- Piperazine Impurity 27 (CAS 7040-23-5)
- Warfarin EP Impurity B (CAS 1076-38-6)
- Ibandronic Impurity 10 (CAS CATO-C4X-224410)
- Loteprednol Impurity 10 (CAS CATO-C4X-195710)
- Gefitinib Impurity 73 (CAS CATO-C4X-111773)
- 2-((4-(2-Chlorophenyl)-6-(4-chlorophenyl)-3-cyanopyridin-2-yl)thio)-N-(4-ethoxyphenyl)acetamide (CAS 332372-36-8)
- N-(Azido-PEG4)-N-Boc-PEG4-NHS ester (CAS 2112731-96-9)
- 2-Chloro-1-ethoxy-3-fluorobenzene (CAS 909122-13-0)
- 2-Bromo-6-propylpyridine-4-carboxylic acid (CAS 76594-14-4)
- 3-Hydroxy-2-(p-tolyl)acrylaldehyde (CAS 53868-45-4)
- 2-Amino-2-(1-Boc-4-piperidyl)acetic Acid (CAS 1421312-30-2)
- Acetyl decapeptide-3 (CAS 935288-50-9)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com