Lifitegrast Impurity 168 CAS CATO-C4X-2409168
| CAS No. | CATO-C4X-2409168 |
| Molecular Formula | C10H8O3 |
| Molecular Weight | 176.17 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies Lifitegrast Impurity 168 (CAS CATO-C4X-2409168), a pharmacopoeial impurity reference standard (molecular formula C10H8O3, MW 176.17 g/mol) used for the identification and quantification of trace impurities in APIs.
Lifitegrast Impurity 168 (C10H8O3) contains a carboxylic acid group, a hydroxyl group, an ether linkage, an aromatic ring system. It is notably hygroscopic, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Lifitegrast Impurity 168 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C10H8O3 |
| Molecular Weight | 176.17 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | ≥95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
Related Lifitegrast Standards
- Lifitegrast Impurity 42 (CAS 588703-29-1)
- Lifitegrast Impurity N60 (CAS 933752-32-0)
- Lifitegrast Impurity 10 (CAS 77095-51-3)
- Lifitegrast Impurity 165 (CAS CATO-C4X-2409165)
- Lifitegrast Impurity 19 (CAS 1289646-90-7)
- Lifitegrast Impurity N68 (CAS 89315-56-0)
- Lifitegrast Impurity 108 (CAS CATO-C4X-2409108)
- Lifitegrast Impurity 109 (CAS CATO-C4X-2409109)
Recommended Standards
- (2-Cyanophenyl)glycine (CAS 64377-71-5)
- Regadenoson Impurity 36 (CAS 871301-32-5)
- 5-Hydroxycoumarin (CAS 53081-42-8)
- Ozagrel Impurity 26 （predominantly trans） (CAS 23359-08-2)
- Teprenone impurity 52 (CAS CATO-C4X-208152)
- Tolvaptan Impurity 104 (CAS CATO-C4X-1955104)
- Sodium aminosalicylate Impurity 5 (CAS 15540-79-1)
- 5,5'-Bis(trimethylstannyl)-2,2'-bithiophene, 99% (CAS 143367-56-0)
- Methyl 5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-2,3-dihydro-1H-indene-1-carboxylate (CAS 1423700-47-3)
- 5-Methyl-1-phenyl-1H-1,2,3-triazole-4-carboxylic acid (CAS 20725-32-0)
- methyl 1-butyl-1H-pyrazole-3-carboxylate (CAS 60056-63-5)
- Dipropylamine 2,2,2-trifluoroacetate (CAS 143651-07-4)
- o-((2-Isopropylthiazol-4-yl)methyl)hydroxylamine (CAS 1539112-10-1)
- Semaglutide Impurity 138 (CAS CATO-C4X-2226138)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com