Lifitegrast Impurity N60 CAS 933752-32-0
| CAS No. | 933752-32-0 |
| Molecular Formula | C10H11NO2 |
| Molecular Weight | 177.20 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Lifitegrast Impurity N60.
Lifitegrast Impurity N60 (CAS 933752-32-0) is a certified pharmaceutical impurity reference standard with the molecular formula C10H11NO2 and a molecular weight of 177.20 g/mol.
Based on its molecular formula C10H11NO2, Lifitegrast Impurity N60 contains an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 177.20 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C10H11NO2 |
| Molecular Weight | 177.20 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Nitrogen Atoms | 1 |
Related Lifitegrast Standards
- Lifitegrast Impurity 168 (CAS CATO-C4X-2409168)
- Lifitegrast Impurity 42 (CAS 588703-29-1)
- Lifitegrast Impurity 19 (CAS 1289646-90-7)
- Lifitegrast Impurity 10 (CAS 77095-51-3)
- Lifitegrast Impurity 165 (CAS CATO-C4X-2409165)
- Lifitegrast Impurity N68 (CAS 89315-56-0)
- Lifitegrast Impurity 108 (CAS CATO-C4X-2409108)
- Lifitegrast Impurity 109 (CAS CATO-C4X-2409109)
Recommended Standards
- 1,2,3,4-Tetrahydro-6-quinolinecarboxylic Acid (CAS 5382-49-0)
- 1,2,3,4-Tetrahydro-isoquinoline-7-carboxylic acid (CAS 526219-52-3)
- 1,2,3,4-Tetrahydro-1-isoquinolinecarboxylic Acid (CAS 41034-52-0)
- 1,2,3,4-Tetrahydroisoquinoline-8-carboxylic acid (CAS 933753-84-5)
- Formoterol Impurity 59 (CAS 306966-56-3)
- Melitracen Impurity 16 (CAS CATO-C4X-120216)
- Adrenaline Impurity 47 (CAS CATO-C4X-184947)
- 2-Amino-2-(5-methoxy-1h-benzo[d]imidazol-2-yl)ethan-1-ol (CAS 1472706-82-3)
- n-((Tetrahydrofuran-2-yl)methyl)-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzamide (CAS 1073355-06-2)
- Celastramycin A (CAS 491600-94-3)
- 2-(3,4-Dimethoxyphenyl)-N-(pyridin-3-ylmethyl)ethan-1-amine (CAS 356093-05-5)
- 3-hydroxy Flubromazepam (CAS 62659-65-8)
- 2-chloro-1-(pyridin-2-yl)ethan-1-one (CAS 55484-10-1)
- Tirzepatide Impurity 51 (CAS CATO-C4X-324051)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com