Fluticasone Impurity 45 CAS 80473-92-3

Description

The occurrence of Fluticasone Impurity 45 is closely related to a flavonoid core, a sulfone group, a hydroxyl group, an ether linkage, fluorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

Fluticasone Impurity 45 (CAS 80473-92-3) is a certified pharmaceutical impurity reference standard with the molecular formula C21H26F2O4S and a molecular weight of 412.49 g/mol.

Owing to a flavonoid core, a sulfone group, a hydroxyl group, an ether linkage, fluorine substitution, Fluticasone Impurity 45 is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 412.49 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.

Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.

CATO manufactures Fluticasone Impurity 45 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.

Physical & Chemical Properties

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