Fluticasone Impurity 57 CAS CATO-C4X-165057
| CAS No. | CATO-C4X-165057 |
| Molecular Formula | C22H28F2O5 |
| Molecular Weight | 410.45 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Fluticasone Impurity 57.
CATO supplies Fluticasone Impurity 57 (CAS CATO-C4X-165057), a pharmacopoeial impurity reference standard (molecular formula C22H28F2O5, MW 410.45 g/mol) used for the identification and quantification of trace impurities in APIs.
Fluticasone Impurity 57 (C22H28F2O5) contains a flavonoid core, a hydroxyl group, an ether linkage, fluorine substitution. Halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO manufactures Fluticasone Impurity 57 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C22H28F2O5 |
| Molecular Weight | 410.45 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | >95% |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | F-containing |
Related Fluticasone Standards
- Fluticasone Impurity 56 (CAS 28416-84-4)
- Fluticasone Impurity 58 (CAS CATO-C4X-165058)
- Fluticasone Impurity 61 (CAS CATO-C4X-165061)
- Fluticasone Impurity 67 (CAS CATO-C4X-165067)
- Fluticasone Impurity 63 (CAS CATO-C4X-165063)
- Fluticasone Impurity 45 (CAS 80473-92-3)
- Fluticasone Propionate USP Related Compound J (CAS 28416-82-2)
- Fluticasone Impurity 60 (CAS CATO-C4X-165060)
Recommended Standards
- tert-butyl-[(1S)-1-(2-iodoethyl)-3-phenyl-propoxy]-dimethyl-silane (CAS 876953-73-0)
- Methyl 2-((6-(adamantan-1-yl)-3-cyano-4-(trifluoromethyl)pyridin-2-yl)thio)acetate (CAS 489463-13-0)
- Cefteram Pivoxil Impurity 3 (CAS 98157-80-3)
- Flumethasone Impurity 1 (CAS 60895-22-9)
- Guaiazulene Impurity 6 (CAS 93914-28-4)
- Ezetimibe Impurity 81 (CAS CATO-C4X-109881)
- Betamethasone impurity 94 (CAS CATO-C4X-143794)
- 1-Methyl 4-prop-2-en-1-yl (2S)-2-{[(9H-fluoren-9-ylmethoxy)carbonyl]amino}butanedioate (CAS 170943-09-6)
- 3-Methyl-5-(1-methyl-1H-pyrazol-5-yl)pyrazolo[1,5-a]pyrimidine-7-carboxylic acid (CAS 1443279-58-0)
- 2-Amino-4-chlorobenzoyl chloride (CAS 1261818-40-9)
- N-(4-(4-((4-chlorophenyl)sulfonyl)piperazin-1-yl)-3-fluorophenyl)acetamide (CAS 866131-34-2)
- 4-Bromo-2-(2,2,2-trifluoroethoxy)benzaldehyde (CAS 1099630-09-7)
- tert-Butyl spiro[indoline-3,4'-piperidine]-1-carboxylate hydrochloride (CAS 1243474-66-9)
- Semaglutide impurity 80 (CAS CATO-C4X-222680)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com