Canagliflozin Impurity 7 CAS 842133-16-8
| CAS No. | 842133-16-8 |
| Molecular Formula | C24H26O5S |
| Molecular Weight | 426.53 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), Canagliflozin Impurity 7 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
As a process- or degradation-related impurity, Canagliflozin Impurity 7 (CAS 842133-16-8, C24H26O5S) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
The molecular framework of Canagliflozin Impurity 7 (C24H26O5S) is characterized by a flavonoid core, a sulfone group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | C24H26O5S |
| Molecular Weight | 426.53 g/mol |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Sulfur Atoms | 1 |
Related Canagliflozin Standards
- Canagliflozin Impurity 28 (CAS CATO-C4X-112328)
- Canagliflozin Impurity 18 (CAS CATO-C4X-112318)
- Canagliflozin Impurity 10 (CAS 1818268-45-9)
- Canagliflozin Impurity 90 (CAS CATO-C4X-112390)
- Canagliflozin Impurity 100 (CAS CATO-C4X-1123100)
- Canagliflozin Impurity 101 (CAS CATO-C4X-1123101)
- Canagliflozin Impurity 58 (CAS CATO-C4X-112358)
- Canagliflozin Impurity 88 (CAS CATO-C4X-112388)
Recommended Standards
- Cariprazine Impurity 63 (CAS CATO-C4X-240863)
- H-Arg(Pbf)-OH (CAS 200115-86-2)
- 2-(Ethyl((5-((6-methyl-3-(1H-pyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl)amino)isothiazol-3-yl)methyl)amino)-2-methylpropan-1-ol (CAS 1094069-99-4)
- D-Arg(Pbf)-OH (CAS 200116-81-0)
- Pregabalin EP Impurity D (CAS 89015-27-0)
- Carbocisteine Impurity 14 TFA (CAS CATO-C4X-201061)
- Avibactam Impurity 157 DiHCl (CAS CATO-C4X-1348157)
- Methyl 6-fluoro-5-hydroxypicolinate (CAS 1256788-43-8)
- 1-[3-(Trifluoromethyl)phenyl]cyclopropanecarbonitrile (CAS 124305-68-6)
- 5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)isoindoline-1,3-dione (CAS 1220423-08-4)
- 2-Bromo-3,5-dichloro-4-methoxypyridine (CAS 1823961-01-8)
- 6-Amino-2-methoxyquinazolin-4(3H)-one (CAS 1379326-88-1)
- (2E)-2-(Benzenesulfonyl)-3-(3-chloro-4-methoxyphenyl)prop-2-enenitrile (CAS 861207-90-1)
- Semaglutide impurity 27 (CAS CATO-C4X-222627)
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