Canagliflozin Impurity 28 CAS CATO-C4X-112328

Purity 97%+In StockPharmacopoeial Impurity Standards
CAS No.CATO-C4X-112328
Molecular FormulaC24H26O5S
Molecular Weight426.53 g/mol
CategoryPharmacopoeial Impurity Standards / EP Impurities
AvailabilityIn Stock

Chemical Structure

Canagliflozin Impurity 28 CAS CATO-C4X-112328 chemical structure

Description

The occurrence of Canagliflozin Impurity 28 is closely related to a flavonoid core, a sulfone group, a hydroxyl group, an ether linkage in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

Canagliflozin Impurity 28 (CAS CATO-C4X-112328) is a certified pharmaceutical impurity reference standard with the molecular formula C24H26O5S and a molecular weight of 426.53 g/mol.

Based on its molecular formula C24H26O5S, Canagliflozin Impurity 28 contains a flavonoid core, a sulfone group, a hydroxyl group, an ether linkage; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 426.53 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC24H26O5S
Molecular Weight426.53 g/mol
Purity97%+
StorageStore at room temperature, protect from light, keep sealed and dry
Solubility (reference)Soluble in methanol, acetonitrile, DMSO, water (slightly soluble)
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)12.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
Sulfur Atoms1

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