Cabozantinib Impurity 21 CAS 849217-49-8
| CAS No. | 849217-49-8 |
| Molecular Formula | C12H12FNO3 |
| Molecular Weight | 237.23 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Cabozantinib Impurity 21 is closely related to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies Cabozantinib Impurity 21 (CAS 849217-49-8), a certified reference material (molecular formula C12H12FNO3, MW 237.23 g/mol) for analytical method development and quality control.
Based on its molecular formula C12H12FNO3, Cabozantinib Impurity 21 contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 237.23 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures Cabozantinib Impurity 21 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C12H12FNO3 |
| Molecular Weight | 237.23 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Cabozantinib Standards
- Cabozantinib 4-Fluorocarbamoyl Methyl Ester Impurity (CAS 1345847-71-3)
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- Cabozantinib Impurity 43 (CAS CATO-C4X-201843)
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Recommended Standards
- 5-(Furan-2-amido)thiophene-2-carboxylic acid (CAS 929972-87-2)
- Methyl 3-(2,5-dioxo-2,5-dihydro-1h-pyrrol-1-yl)thiophene-2-carboxylate (CAS 465514-23-2)
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- Methyl 4-nitrobenzo[b]thiophene-2-carboxylate (CAS 34084-87-2)
- Ethyl 2-(3-chlorophenyl)oxazole-4-carboxylate (CAS 132089-43-1)
- 2-Chloro-N-(pyridin-3-yl)acetamide hydrochloride (CAS 181825-64-9)
- Ethyl 4-isopropylisoxazole-3-carboxylate (CAS 1332635-53-6)
- 87630-37-3 Oxo-(1-triisopropylsilyl-1h-pyrrol-3-yl)acetic acid ethyl ester (CAS 87630-37-3)
- Methyl 2,4-dichloro-5-fluorophenylacetate (CAS 1803807-88-6)
- 2,4,5,6-Tetramethylbenzenedisulfonyl Dichloride (CAS 97997-76-7)
- Cefazolin Impurity 44 (CAS 20198-75-8)
- Dabigatran Impurity 40 (CAS CATO-C4X-108940)
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- D-Lys20-Tirzepatide (CAS CATO-CPTD788914)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com