Hydrocortisone EP Impurity G CAS 906337-64-2

Purity >90%In StockPharmacopoeial Impurity Standards
CAS No.906337-64-2
Molecular FormulaC21H28O5
Molecular WeightN/A
CategoryPharmacopoeial Impurity Standards / EP Impurities
AvailabilityIn Stock

Chemical Structure

Hydrocortisone EP Impurity G CAS 906337-64-2 chemical structure

Description

Hydrocortisone EP Impurity G (CAS 906337-64-2) is a certified pharmaceutical impurity reference standard with the molecular formula C21H28O5H2O and a molecular weight of 378.46 g/mol.

Structurally, Hydrocortisone EP Impurity G (C21H28O5H2O) contains a flavonoid core, a hydroxyl group, an ether linkage. The molecule exhibits a degree of unsaturation (DBE) of 7.0, corresponding to approximately 7 ring(s) or double-bond equivalent(s). With a molecular weight of 378.46 g/mol, it falls into the moderately-high-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC21H28O5 H2O
Molecular Weight378.46 g/mol
AppearanceOff-white to pale yellow crystalline powder
Purity>90%
StorageStore at 2-8°C, protect from light, keep sealed and dry
Solubility (reference)Soluble in methanol, acetonitrile, DMSO, water (slightly soluble)
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)7.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1987

Related Hydrocortisone Standards

Recommended Standards

Why CATO?