Hydrocortisone EP Impurity I CAS 103795-84-2
| CAS No. | 103795-84-2 |
| Molecular Formula | C21H30O6 |
| Molecular Weight | 378.46 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Based on its molecular formula C21H30O6, Hydrocortisone EP Impurity I contains a flavonoid core, a hydroxyl group, an ether linkage; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 378.46 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
CATO supplies Hydrocortisone EP Impurity I (CAS 103795-84-2), a pharmacopoeial impurity reference standard (molecular formula C21H30O6, MW 378.46 g/mol) used for the identification and quantification of trace impurities in APIs.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Hydrocortisone EP Impurity I meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C21H30O6 |
| Molecular Weight | 378.46 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1986 |
Related Hydrocortisone Standards
- Hydrocortisone EP Impurity O (CAS 154032-37-8)
- Hydrocortisone Impurity 21 (CAS 68473-77-8)
- Hydrocortisone EP Impurity D (CAS 53-35-0)
- Hydrocortisone EP Impurity H (CAS CATO-C4X-14018)
- Hydrocortisone 21-Carboxylic Acid (CAS 57172-48-2)
- Hydrocortisone Impurity 65 (CAS CATO-C4X-140165)
- Hydrocortisone Impurity 71 (CAS 37413-94-8)
- Hydrocortisone EP Impurity E (CAS 7753-60-8)
Recommended Standards
- Lotilaner Impurity 15 (CAS CATO-C4X-325615)
- Neotame (CAS 165450-17-9)
- Z-Leu-Leu-OH (CAS 7801-71-0)
- 18-Hydroxycortisol (CAS 81705-06-8)
- Gefitinib Impurity 48 (CAS 1006378-06-8)
- Tadalafil Impurity 57 (CAS CATO-C4X-108757)
- Brivaracetam Impurity 179 (CAS CATO-C4X-2007179)
- Adenine Impurity 17 (CAS 91279-78-6)
- 2-Cyclopropyl-5,6,7,8-tetrahydro-[1,2,4]triazolo[1,5-a]pyrazine (CAS 681249-78-5)
- 5-(Cyanomethyl)benzo[d]oxazole-2-carboxylic acid (CAS 1804209-86-6)
- 2,6-Dimethoxy-3-(trimethylsilyl)pyridine (CAS 1373693-69-6)
- 1-((2-Methoxy-5-methylphenyl)sulfonyl)-2-methyl-1H-imidazole (CAS 325992-06-1)
- 6-Methoxy-2-phenylquinazoline (CAS 34637-66-6)
- Semaglutide impurity 58 (CAS CATO-C4X-222658)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com