Celecoxib Impurity 45 CAS 90824-33-2
| CAS No. | 90824-33-2 |
| Molecular Formula | C6H9N3O2S |
| Molecular Weight | 187.22 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a process- or degradation-related impurity, Celecoxib Impurity 45 (CAS 90824-33-2, C6H9N3O2S) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
The molecular framework of Celecoxib Impurity 45 (C6H9N3O2S) is characterized by an amide group, a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Celecoxib Impurity 45 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C6H9N3O2S |
| Molecular Weight | 187.22 g/mol |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1982 |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Related Celecoxib Standards
Recommended Standards
- Timolol EP Impurity D (CAS 30165-97-0)
- Benzenesulfonic Impurity 4 (CAS 55034-26-9)
- Vonoprazan Impurity 57 (CAS 2726830-13-1)
- Dotinurad Impurity 171 (CAS 50910-59-3)
- Lacidipine Impurity 30 (E-Isomer) (CAS 187947-49-5)
- Alogliptin Impurity 96 (CAS CATO-C4X-109996)
- Dutasteride impurity G (CAS 433-19-2)
- tert-Butyl Sulfide (CAS 107-47-1)
- 1-(Cyclopropylmethyl)-1h-benzo[d]imidazole-4-carboxylic acid (CAS 1547187-44-9)
- 4-Chloro-2-(((3,4-dichlorophenyl)amino)methyl)phenol (CAS 1036472-12-4)
- 2-[(2-methylphenyl)methoxy]acetic acid (CAS 953786-96-4)
- Dipyridamole EP Impurity C (CAS 54093-92-4)
- 4-Methyl-6-(piperazin-1-yl)nicotinic acid (CAS 1355179-96-2)
- Ac-(5-31)Semaglutide (CAS CATO-C4X-2226279)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com