Celecoxib Impurity 35 CAS 98-64-6
| CAS No. | 98-64-6 |
| Molecular Formula | C6H6ClNO2S |
| Molecular Weight | 191.64 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a process- or degradation-related impurity, Celecoxib Impurity 35 (CAS 98-64-6, C6H6ClNO2S) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
The molecular framework of Celecoxib Impurity 35 (C6H6ClNO2S) is characterized by an amide group, a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
CATO manufactures Celecoxib Impurity 35 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C6H6ClNO2S |
| Molecular Weight | 191.64 g/mol |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Related Celecoxib Standards
- Celecoxib Impurity 34 (CAS 24939-24-0)
- Celecoxib Impurity N3 (CAS 877-67-8)
- Celecoxib Impurity 38 (CAS 131774-72-6)
- Celecoxib Impurity 40 (CAS 4392-54-5)
- Celecoxib Impurity 45 (CAS 90824-33-2)
- Celecoxib Impurity N4 (CAS 90829-71-3)
- Celecoxib Impurity 27 (CAS 343853-74-7)
- Celecoxib Impurity 62 (CAS CATO-C4X-104362)
Recommended Standards
- 4-chloro-1-methyl-pyrazolo[3,4-d]pyrimidin-6-amine (CAS 100644-66-4)
- Pyridin-2-ylmethanesulfonyl chloride (CAS 540523-41-9)
- (3R,5S)-3-(3-Chloropropyl)-5-(hydroxymethyl)pyrrolidin-2-one (CAS 1013937-92-2)
- N-Chlorobenzenesulfonamide (CAS 80-16-0)
- Fovinaciclib Impurity 4 (CAS CATO-C4X-33864)
- Dapagliflozin Impurity 192 (CAS CATO-C4X-1138192)
- Ketorolac Impurity 52 (CAS 147088-89-9)
- Talazoparib Impurity 4 (CAS 1322879-81-1)
- 3-(2-(4-Fluorophenyl)-7-methylimidazo[1,2-a]pyridin-3-yl)acrylic acid (CAS 727652-29-1)
- Risdiplam (CAS 1825352-65-5)
- H-D-Asp(OtBu)-AMC (CAS 2044711-03-5)
- Pyrazine-2-sulfonyl fluoride (CAS 2090368-34-4)
- 2-(Difluoromethyl)-3-hydroxy-6-methylisonicotinonitrile (CAS 1806947-02-3)
- Myelin Basic Protein (85-99) Peptide Antagonist (CAS 444305-16-2)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com