Celecoxib Impurity N3 CAS 877-67-8
| CAS No. | 877-67-8 |
| Molecular Formula | C6H8N2O3S |
| Molecular Weight | 188.20 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO manufactures Celecoxib Impurity N3 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Celecoxib Impurity N3 (CAS 877-67-8) is a certified pharmaceutical impurity reference standard with the molecular formula C6H8N2O3S and a molecular weight of 188.20 g/mol.
Structurally, Celecoxib Impurity N3 (C6H8N2O3S) contains an amide group, a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, an aromatic ring system. The molecule exhibits a degree of unsaturation (DBE) of 4.0, corresponding to approximately 4 ring(s) or double-bond equivalent(s). With a molecular weight of 188.20 g/mol, it falls into the medium-molecular-weight range. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | C6H8N2O3S |
| Molecular Weight | 188.20 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO, water |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related Celecoxib Standards
- Celecoxib Impurity 38 (CAS 131774-72-6)
- Celecoxib Impurity 40 (CAS 4392-54-5)
- Celecoxib Impurity 45 (CAS 90824-33-2)
- Celecoxib Impurity N4 (CAS 90829-71-3)
- Celecoxib Impurity 34 (CAS 24939-24-0)
- Celecoxib Impurity 35 (CAS 98-64-6)
- Celecoxib Impurity 3 (CAS 53578-01-1)
- Celecoxib Impurity 27 (CAS 343853-74-7)
Recommended Standards
- 8-fluoroimidazo[1,5-a]pyridine-5-carboxylic acid (CAS 2168375-14-0)
- Ethyl 2-amino-4-hydroxythiazole-5-carboxylate (CAS 72218-74-7)
- 7-FLUOROIMIDAZO[1,2-A]PYRIDINE-2-CARBOXYLIC ACID (CAS 886363-98-0)
- Ethyl 2-imino-4-oxo-1,3-thiazolidine-5-carboxylate (CAS 5425-41-2)
- Methylprednisolone EP Impurity J (CAS 53-36-1)
- Ritalin impurity 6 (CAS 24321-14-0)
- Ranitidine Impurity 20 (CAS 82301-45-9)
- tert-Butyl N-{3-azabicyclo[4.1.0]heptan-1-yl}carbamate (CAS 134575-47-6)
- (5-Cyclopropoxy-6-methoxypyridin-3-yl)methanamine (CAS 1243381-80-7)
- (S)-2-(3-(diisopropylamino)-1-phenylpropyl)-4-(hydroxymethyl)phenol (CAS 260389-90-0)
- 1-(Tert-butyl) 2-ethyl (2S,5S)-5-methylpyrrolidine-1,2-dicarboxylate (CAS 676560-83-1)
- Methyl 4-Hydroxypyrimidine-5-carboxylate (CAS 4774-35-0)
- 1,8-Naphthyridine-4-carbonitrile (CAS 1142927-41-0)
- Allo-D-Ile17-Tirzepatide (CAS CATO-CPTD788962)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com