Cloxacillin Impurity 17 CAS 91059-01-7

Purity >75%In StockPharmacopoeial Impurity Standards
CAS No.91059-01-7
Molecular FormulaC11H7Cl2NO2
Molecular Weight256.08 g/mol
CategoryPharmacopoeial Impurity Standards / EP Impurities
AvailabilityIn Stock

Chemical Structure

Cloxacillin Impurity 17 CAS 91059-01-7 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 256.08 g/mol gives Cloxacillin Impurity 17 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

CATO supplies Cloxacillin Impurity 17 (CAS 91059-01-7), a pharmacopoeial impurity reference standard (molecular formula C11H7Cl2NO2, MW 256.08 g/mol) used for the identification and quantification of trace impurities in APIs.

The molecular framework of Cloxacillin Impurity 17 (C11H7Cl2NO2) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC11H7Cl2NO2
Molecular Weight256.08 g/mol
AppearancePale yellow to yellow crystalline powder. (slight halide-like odor, low volatility)
Purity>75%
StorageStore at 2-8°C, protect from light, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in chloroform, dichloromethane, ethyl acetate, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)8.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1983
Halogen ContentCl-containing
Nitrogen Atoms1

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