Nebivolol Impurity 26 CAS 93340-05-7
| CAS No. | 93340-05-7 |
| Molecular Formula | C10H9FO3 |
| Molecular Weight | 196.18 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a process- or degradation-related impurity, Nebivolol Impurity 26 (CAS 93340-05-7, C10H9FO3) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
The molecular framework of Nebivolol Impurity 26 (C10H9FO3) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO manufactures Nebivolol Impurity 26 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C10H9FO3 |
| Molecular Weight | 196.18 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1983 |
| Halogen Content | F-containing |
Related Nebivolol Standards
- Nebivolol Impurity 25 (CAS 944904-25-0)
- Nebivolol Impurity 42 (CAS 197706-50-6)
- Nebivolol Impurity 43 (CAS 129050-23-3)
- Nebivolol Impurity 44 (CAS 197706-51-7)
- Nebivolol Impurity 45 (CAS 129050-26-6)
- Nebivolol Impurity 74 (CAS CATO-C4X-196874)
- Nebivolol Impurity 1 (CAS 1346562-34-2)
- Nebivolol Impurity 20 (CAS 105300-40-1)
Recommended Standards
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- Dacomitinib Impurity 52 (CAS CATO-C4X-208652)
- Caspofungin Impurity E Diacetate Salt (CAS CATO-C4X-157527)
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- 3-(4-Aminophenoxy)benzonitrile (CAS 305801-18-7)
- 4-(1-Pyrazolyl)benzylamine (CAS 368870-03-5)
- Tert-butyl (r)-(1-cyclohexylpyrrolidin-3-yl)carbamate (CAS 762285-78-9)
- Thieno[3,2-f]quinoline-2-carboxylic acid (CAS 1619264-46-8)
- 3-(4-Phenylbenzoyl)pyridine (CAS 123734-38-3)
- 4-(3-Hydroxy-1-(3-(trifluoromethyl)phenyl)propyl)thiomorpholine 1,1-dioxide (CAS 866041-22-7)
- Semaglutide Impurity 158 (x TFA Salt) (CAS CATO-C4X-2226158)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com