Sitagliptin-N-sulfate CAS 940002-57-3
| CAS No. | 940002-57-3 |
| Molecular Formula | C16H15F6N5O4S |
| Molecular Weight | 487.38 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Sitagliptin-N-sulfate (CAS 940002-57-3) is a high-purity analytical reference standard with the molecular formula C16H15F6N5O4S and a molecular weight of 487.38 g/mol.
Owing to a flavonoid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine substitution, Sitagliptin-N-sulfate is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 487.38 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), Sitagliptin-N-sulfate meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C16H15F6N5O4S |
| Molecular Weight | 487.38 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 5 |
| Sulfur Atoms | 1 |
Related Sitagliptin Standards
- Sitagliptin Impurity 25 (CAS CATO-C4X-114425)
- Sitagliptin Impurity 128 (CAS CATO-C4X-1144128)
- Sitagliptin Impurity 104 (CAS CATO-C4X-1144104)
- Sitagliptin Impurity 161 (CAS 1608491-98-0)
- Sitagliptin impurity 143 (CAS CATO-C4X-1144143)
- Sitagliptin impurity 146 (CAS CATO-C4X-1144146)
- Sitagliptin Impurity 87 (CAS CATO-C4X-114487)
- Sitagliptin Impurity 149 (CAS CATO-C4X-1144149)
Recommended Standards
- N-(3-Chloro-4-fluorophenyl)-2-((5-(4-chlorophenyl)-4-(p-tolyl)-4H-1,2,4-triazol-3-yl)thio)acetamide (CAS 477330-53-3)
- Terbutaline impurity 100 (CAS CATO-C4X-1183100)
- Azido-PEG5-CH2CO2-PFP (CAS 2144777-92-2)
- 6-Bromo-9-phenyl-9H-3,9'-bicarbazole (CAS 1313431-76-3)
- Tert-butyl (1R,2R,5S)-2-(hydroxymethyl)-6,6-dimethyl-3-azabicyclo[3.1.0]Hexane-3-carboxylate (CAS 2101518-51-6)
- 5-[(4-chloro-1h-pyrazol-1-yl)methyl]thiophene-2-carboxylic acid (CAS 1006455-24-8)
- Methyl 4-methoxy-6,7-dihydro-5H-pyrrolo[3,4-d]pyrimidine-2-carboxylate (CAS 2409488-54-4)
- 5-((1H-1,2,4-Triazol-3-yl)thio)-2-nitroaniline (CAS 55564-45-9)
- 1-(4,5-Dihydro-1H-imidazol-2-yl)isoquinoline (CAS 63656-90-6)
- (R)-2-(3,3-difluorocyclohexyl)acetic acid (CAS 2231664-80-3)
- Mast Cell Degranulating (MCD) Peptide (CAS 32908-73-9)
- 5-Morpholinopyrazine-2-carboxylic acid (CAS 946598-39-6)
- Ethyl 2-(2-(methylamino)pyrimidin-4-yl)-1H-indole-5-carboxylate (CAS 916486-06-1)
- Semaglutide impurity 80 (CAS CATO-C4X-222680)
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