Riociguat Impurity 9 CAS 956010-88-1
| CAS No. | 956010-88-1 |
| Molecular Formula | C7H4N4 |
| Molecular Weight | 144.13 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 144.13 g/mol gives Riociguat Impurity 9 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
As a process- or degradation-related impurity, Riociguat Impurity 9 (CAS 956010-88-1, C7H4N4) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Structurally, Riociguat Impurity 9 (C7H4N4) contains a nitrile group, an aromatic ring system. The molecule exhibits a degree of unsaturation (DBE) of 8.0, corresponding to approximately 8 ring(s) or double-bond equivalent(s). With a molecular weight of 144.13 g/mol, it falls into the low-molecular-weight range. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C7H4N4 |
| Molecular Weight | 144.13 g/mol |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Nitrogen Atoms | 4 |
Related Riociguat Standards
- Riociguat Impurity N13 (CAS 6017-21-6)
- Riociguat Impurity 13 (CAS CATO-C4X-174913)
- Riociguat Impurity 8 (CAS 256376-65-5)
- Riociguat Impurity N10 (CAS 2101651-50-5)
- Riociguat Impurity N3 (CAS 2512205-25-1)
- Riociguat Impurity 24 (CAS 256376-62-2)
- Riociguat Impurity 24 (CAS 93866-45-6)
- Riociguat Impurity 26 (CAS 304874-06-4)
Recommended Standards
- Allopurinol impurity 15 (CAS CATO-C4X-145815)
- Dimethyl Maleate (CAS 624-48-6)
- N-Nitroso Nifedipine EP Impurity D (CAS CATO-C4X-141033)
- 3,4-Dideoxyglucosone-3-ene (CAS 252006-38-5)
- Cariprazine Impurity 67 (CAS CATO-C4X-240867)
- Carbidopa impurity 38 (CAS 2470439-16-6)
- Olmesartan Impurity 80 (CAS 752179-89-8)
- 5-Methoxy-2,2-dimethylbenzo[d][1,3]dioxole (CAS 101911-24-4)
- 2-Fluoro-5-methoxybiphenyl (CAS 1214331-90-4)
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- 1-(Pyrimidin-2-yl)pyrrolidin-3-ol (CAS 1261229-76-8)
- 4-(3-azetidinyl)-Thiomorpholine 1,1-dioxide, 2,2,2-trifluoroacetate (1:2) (CAS 1980064-31-0)
- (R)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-2-([1,1'-biphenyl]-4-yl)acetic acid (CAS 1260601-97-5)
- Liraglutide Impurity 17 TFA Salt (CAS CATO-C4X-199217)
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