Hydrochlorothiazide Impurity 13 CAS 99418-26-5
| CAS No. | 99418-26-5 |
| Molecular Formula | C6H6ClNO6S2 |
| Molecular Weight | 287.70 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Hydrochlorothiazide Impurity 13 (C6H6ClNO6S2) contains a carbohydrate-derived structure, an amide group, a sulfone group, chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Hydrochlorothiazide Impurity 13 (CAS 99418-26-5) is a certified pharmaceutical impurity reference standard with the molecular formula C6H6ClNO6S2 and a molecular weight of 287.70 g/mol.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Hydrochlorothiazide Impurity 13 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C6H6ClNO6S2 |
| Molecular Weight | 287.70 g/mol |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO, water |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1985 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 2 |
Related Hydrochlorothiazide Standards
- Hydrochlorothiazide impurity 44 (CAS CATO-C4X-117744)
- Hydrochlorothiazide Impurity 52 (CAS CATO-C4X-117752)
- Hydrochlorothiazide EP Impurity B (CAS 121-30-2)
- Hydrochlorothiazide Impurity 22 (CAS 90794-87-9)
- Hydrochlorothiazide Impurity 56 (CAS CATO-C4X-117756)
- Hydrochlorothiazide EP Impurity A (CAS 58-94-6)
- Hydrochlorothiazide Impurity 20 (CAS 82205-98-9)
- Hydrochlorothiazide (CAS 58-93-5)
Recommended Standards
- α-Desmethyl Benoxaprofen (CAS 51234-85-6)
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- Triamterene RC 1 (CAS 16470-02-3)
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- Folic Acid Impurity 31 (CAS CATO-C4X-139531)
- Elobixibat Impurity 24 (CAS CATO-C4X-283824)
- 5-(Cyclopentylmethyl)-3-methylisoxazole (CAS 921588-52-5)
- Tert-butyl (r)-(1-(cyclohexanecarbonyl)pyrrolidin-3-yl)carbamate (CAS 1286207-95-1)
- 6-Formylpyridine-2-carboxylic Acid (CAS 499214-11-8)
- Methyl (2S,4S)-4-(4-chloro-2-ethylphenoxy)-2-pyrrolidinecarboxylate hydrochloride (CAS 1354488-02-0)
- 4-ethyl-4-methoxy-piperidine;hydrochloride (CAS 1803587-00-9)
- (4-Ethyl-4,5-dihydrooxazol-4-yl)methanol (CAS 57101-67-4)
- Cholecystokinin Octapeptide (1-4) (desulfated) (CAS 80790-40-5)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com