Lorazepam Impurity 13 CAS CATO-C4X-104113
| CAS No. | CATO-C4X-104113 |
| Molecular Formula | C28H18Cl4N2O3 |
| Molecular Weight | 572.27 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Based on its molecular formula C28H18Cl4N2O3, Lorazepam Impurity 13 contains a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 572.27 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Lorazepam Impurity 13 (CAS CATO-C4X-104113) is a certified pharmaceutical impurity reference standard with the molecular formula C28H18Cl4N2O3 and a molecular weight of 572.27 g/mol.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Lorazepam Impurity 13 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C28H18Cl4N2O3 |
| Molecular Weight | 572.27 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 19.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Lorazepam Standards
- Lorazepam Impurity 19 (CAS CATO-C4X-104119)
- Lorazepam Impurity 8 (CAS 2848-96-6)
- Lorazepam Impurity 20 (CAS CATO-C4X-104120)
- Lorazepam impurity 9 (CAS CATO-C4X-10419)
- Lorazepam Impurity 18 (CAS CATO-C4X-104118)
- Lorazepam-D4 (CAS 84344-15-0)
- Lorazepam Impurity 14 (CAS CATO-C4X-104114)
- Lorazepam Impurity 15 (CAS CATO-C4X-104115)
Recommended Standards
- Crisaborole Impurity 147 (CAS CATO-C4X-2021147)
- (S)-Ethyl 2-((tert-butoxycarbonyl)amino)-3-(5-((tert-butoxycarbonyl)-oxy)-2-(trimethylstannyl)phenyl)propanoate (CAS 845882-24-8)
- Crisaborole Impurity 145 (CAS CATO-C4X-2021145)
- N-((5-((4-Bromobenzyl)thio)-4-(4-bromophenyl)-4H-1,2,4-triazol-3-yl)methyl)-2-phenylacetamide (CAS 389071-51-6)
- Glucosamine sulfate impurity 20 (CAS CATO-C4X-194620)
- Apixaban Impurity 44 (CAS 536759-91-8)
- Cholic Acid Impurity 30 (CAS 1093397-66-0)
- 6-Bromo-5-chloropicolinic acid (CAS 1214328-42-3)
- 1-(2,2-diethoxyethyl)-1H-1,2,3-triazole-4-carboxylic acid (CAS 1235440-33-1)
- 6-Bromo-2-methyl-2H-indazole-3-sulfonyl chloride (CAS 1363380-61-3)
- 2-Amino-3-(2,3-difluoro-4-methoxyphenyl)propanoic acid (CAS 1256482-63-9)
- Galiellalactone (CAS 133613-71-5)
- Levamisol Hydrochloride (CAS 16595-80-5)
- C-Peptide 2 (rat) (CAS 41594-08-5)
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