Regorafenib Impurity 51 CAS CATO-C4X-104751
| CAS No. | CATO-C4X-104751 |
| Molecular Formula | C13H12FN3O2 |
| Molecular Weight | 261.25 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO manufactures Regorafenib Impurity 51 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Regorafenib Impurity 51 (CAS CATO-C4X-104751) is a certified pharmaceutical impurity reference standard with the molecular formula C13H12FN3O2 and a molecular weight of 261.25 g/mol.
The molecular framework of Regorafenib Impurity 51 (C13H12FN3O2) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Physical & Chemical Properties
| Molecular Formula | C13H12FN3O2 |
| Molecular Weight | 261.25 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
Related Regorafenib Standards
- Regorafenib EP Impurity A (CAS 757251-39-1)
- Regorafenib Impurity 32 (CAS CATO-C4X-104732)
- Regorafenib Impurity 36 (CAS 864245-61-4)
- Regorafenib Impurity 40 (CAS CATO-C4X-104740)
- Regorafenib Impurity 48 (CAS CATO-C4X-104748)
- Regorafenib Impurity 40 (CAS 2711-18-4)
- Regorafenib Impurity 43 (CAS 1798046-84-0)
- Regorafenib Impurity 5 (CAS 19448-54-5)
Recommended Standards
- Flumequine (CAS 42835-25-6)
- H-Tyr(SO3H)-OH (CAS 956-46-7)
- Flupirtine Impurity 4 (CAS 1506942-35-3)
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- Ertapenem Impurity 53 (CAS CATO-C4X-163353)
- Clopidogrel Impurity 103 (CAS CATO-C4X-1029103)
- Ceftazidime Impurity 24 (CAS CATO-C4X-121224)
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- 4-[(2,6-dimethylphenyl)carbamoyl]butanoic acid (CAS 201137-73-7)
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- n-(2,3-Difluorobenzyl)cyclopropanamine (CAS 625437-45-8)
- Imidazo[1,2-a]pyridine-2,6-dicarboxylic acid, 2,6-diethyl ester (CAS 1956354-97-4)
- Neuropeptide Y (human, rat) trifluoroacetate salt (CAS 90880-35-6)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com