Ibrutinib Impurity 167 CAS CATO-C4X-1064167

Description

The occurrence of Ibrutinib Impurity 167 is closely related to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

Ibrutinib Impurity 167 (CAS CATO-C4X-1064167) is a certified pharmaceutical impurity reference standard with the molecular formula C42H42N10O2HCl and a molecular weight of 755.32 g/mol.

Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution, Ibrutinib Impurity 167 is typically pale yellow to yellow amorphous powder. Its solid-state physicochemical attributes — including a molecular weight of 755.32 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.

CATO manufactures Ibrutinib Impurity 167 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.

Physical & Chemical Properties

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