Ibrutinib Impurity 60 CAS CATO-C4X-106460
| CAS No. | CATO-C4X-106460 |
| Molecular Formula | C34H42N8O3 |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, Ibrutinib Impurity 60 is typically pale yellow to yellow amorphous powder. Its solid-state physicochemical attributes — including a molecular weight of 610.76 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
As a process- or degradation-related impurity, Ibrutinib Impurity 60 (CAS CATO-C4X-106460, C34H42N8O3) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Ibrutinib Impurity 60 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C34H42N8O3 |
| Molecular Weight | 610.76 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 18.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 8 |
Related Ibrutinib Standards
- Ibrutinib Impurity 47 (CAS 1022150-11-3)
- Ibrutinib Impurity 10 (CAS 1022150-12-4)
- Ibrutinib Impurity 80 (CAS 109384-19-2)
- Ibrutinib Impurity 53 (CAS 109831-68-7)
- Ibrutinib Impurity 54 (CAS 1260862-85-8)
- Ibrutinib Impurity 4 (CAS 1288338-95-3)
- Ibrutinib Impurity 3 (CAS 1288338-96-4)
- Ibrutinib Impurity 81 (CAS 143667-36-1)
Recommended Standards
- Abiraterone Impurity 21 (CAS 1620323-43-4)
- Palbociclib Impurity 15 (CAS CATO-C3D-1458)
- Imrecoxib Impurity 69 (CAS 3323-79-3)
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- (D-Trp32)-Neuropeptide Y (porcine) trifluoroacetate salt (CAS 153549-78-1)
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