Tofacitinib Impurity 210 CAS CATO-C4X-1079210
| CAS No. | CATO-C4X-1079210 |
| Molecular Formula | C20H25N7O3 |
| Molecular Weight | 411.46 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Tofacitinib Impurity 210 (CAS CATO-C4X-1079210) is a certified pharmaceutical impurity reference standard with the molecular formula C20H25N7O3 and a molecular weight of 411.46 g/mol.
Tofacitinib Impurity 210 (C20H25N7O3) contains a steroid core, an amide group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
As a certified reference material (CRM), Tofacitinib Impurity 210 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C20H25N7O3 |
| Molecular Weight | 411.46 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 7 |
Related Tofacitinib Standards
- Tofacitinib Impurity 163 (CAS CATO-C4X-1079163)
- Tofacitinib Impurity 8 (CAS CATO-C4X-10798)
- Tofacitinib Impurity 19 (CAS CATO-C4X-107919)
- Tofacitinib Impurity 148 (CAS CATO-C4X-1079148)
- Tofacitinib Impurity 152 (CAS CATO-C4X-1079152)
- Tofacitinib Impurity 105 (CAS 2459302-85-1)
- Tofacitinib Impurity 241 (CAS CATO-C4X-1079241)
- Tofacitinib Impurity 244 (CAS 2504210-48-2)
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- 5-Bromo-4-chloro-2,6-diphenylpyrimidine (CAS 40780-01-6)
- 5-Fluoro-2-(3-fluorophenyl)pyridine (CAS 511522-72-8)
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