Clofazimine Impurity 28 CAS CATO-C4X-207128
| CAS No. | CATO-C4X-207128 |
| Molecular Formula | C24H16Cl2N4 |
| Molecular Weight | 431.32 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Clofazimine Impurity 28 (CAS CATO-C4X-207128) is a certified pharmaceutical impurity reference standard with the molecular formula C24H16Cl2N4 and a molecular weight of 431.32 g/mol.
Based on its molecular formula C24H16Cl2N4, Clofazimine Impurity 28 contains a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 431.32 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C24H16Cl2N4 |
| Molecular Weight | 431.32 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 18.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 4 |
Related Clofazimine Standards
- Clofazimine Impurity 26 (CAS CATO-C4X-207126)
- Clofazimine Impurity 29 (CAS CATO-C4X-207129)
- Clofazimine EP Impurity A (CAS 102262-55-5)
- Clofazimine Impurity 9 (CAS 96762-04-8)
- Clofazimine Impurity 3 (CAS 90712-89-3)
- Clofazimine Impurity 14 (CAS CATO-C4X-207114)
- Clofazimine Impurity 17 (CAS CATO-C4X-207117)
- Clofazimine Impurity 2 (CAS 2158184-11-1)
Recommended Standards
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