Clofazimine Impurity 26 CAS CATO-C4X-207126
| CAS No. | CATO-C4X-207126 |
| Molecular Formula | C24H16Cl2N4 |
| Molecular Weight | 431.32 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Clofazimine Impurity 26.
CATO supplies Clofazimine Impurity 26 (CAS CATO-C4X-207126), a pharmacopoeial impurity reference standard (molecular formula C24H16Cl2N4, MW 431.32 g/mol) used for the identification and quantification of trace impurities in APIs.
Clofazimine Impurity 26 (C24H16Cl2N4) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Clofazimine Impurity 26 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C24H16Cl2N4 |
| Molecular Weight | 431.32 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 18.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 4 |
Related Clofazimine Standards
- Clofazimine Impurity 28 (CAS CATO-C4X-207128)
- Clofazimine Impurity 29 (CAS CATO-C4X-207129)
- Clofazimine EP Impurity A (CAS 102262-55-5)
- Clofazimine Impurity 9 (CAS 96762-04-8)
- Clofazimine Impurity 3 (CAS 90712-89-3)
- Clofazimine Impurity 14 (CAS CATO-C4X-207114)
- Clofazimine Impurity 17 (CAS CATO-C4X-207117)
- Clofazimine Impurity 2 (CAS 2158184-11-1)
Recommended Standards
- Tofacitinib Impurity 211 (CAS CATO-C4X-1079211)
- 4-Chloro-5-(4-(3-chlorophenyl)piperazin-1-yl)-2-(4-methoxyphenyl)pyridazin-3(2H)-one (CAS 477867-46-2)
- 2-Bromo-6-(7,7-dimethyl-1-oxo-1,3,4,6,7,8-hexahydro-2H-cyclopenta[4,5]pyrrolo[1,2-a]pyrazin-2-yl)benzyl acetate (CAS 1346674-24-5)
- tert-Butyl 3-((5-bromo-3-(dimethoxymethyl)pyridin-2-yloxy)methyl)pyrrolidine-1-carboxylate (CAS 1186311-12-5)
- Ketoconazole EP Impurity E (CAS 134071-44-6)
- Loratadine Impurity 61 (CAS CATO-C4X-142661)
- Sugammadex Impurity 38 (CAS CATO-C4X-190638)
- 2-(6,7,8,9-Tetrahydro-5H-[1,2,4]triazolo[4,3-a]azepin-3-yl)ethanamine (CAS 923255-73-6)
- 3-(Chloromethyl)-6-methylpyridazin-4(1H)-one (CAS 17417-54-8)
- (R)-1-(4-ethoxyphenyl)ethan-1-amine (CAS 856758-56-0)
- 6-Phenyl-1H-pyrazolo[3,4-d]pyrimidin-4-amine (CAS 21319-23-3)
- 2-(3-(Dimethylamino)phenyl)butan-2-ol (CAS 1379337-55-9)
- H-Ala-Tyr-OH (CAS 3061-88-9)
- Semaglutide impurity 206 (CAS CATO-C4X-2226206)
Why CATO?
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