Amlodipine Impurity 74 CAS CATO-C4X-109574
| CAS No. | CATO-C4X-109574 |
| Molecular Formula | 2*C20H25ClN2O5 |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 408.88 g/mol gives Amlodipine Impurity 74 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
Amlodipine Impurity 74 (CAS CATO-C4X-109574) is a certified pharmaceutical impurity reference standard with the molecular formula C20H25ClN2O5 and a molecular weight of 408.88 g/mol.
Owing to a flavonoid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution, Amlodipine Impurity 74 is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 408.88 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Amlodipine Impurity 74 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | 2*C20H25ClN2O5 |
| Molecular Weight | 408.88 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Amlodipine Standards
- Amlodipine Impurity N32 (CAS 103094-30-0)
- (R)-Amlodipine (CAS 103129-81-3)
- Amlodipine (S)-Isomer (CAS 103129-82-4)
- Amlodipine Impurity N5 (CAS 107812-86-2)
- Amlodipine Impurity N2 (CAS 111429-90-4)
- Amlodipine Besylate (CAS 111470-99-6)
- Amlodipine Impurity N4 (CAS 113994-36-8)
- Amlodipine Impurity 38 (CAS 113994-37-9)
Recommended Standards
- Minoxidil Impurity 38 (CAS CATO-C4X-170038)
- Isavuconazole Impurity 142 (CAS CATO-C4X-1236142)
- Haloperidol Impurity 21 (CAS 3874-54-2)
- Ethyl 2-chloro-4-iodobenzoate (CAS 92712-69-1)
- 5-Methyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carboxylic acid (CAS 331647-99-5)
- 1-(4-Iodophenyl)-4,4-dimethyl-1,4-dihydropyrimidine-2-thiol (CAS 1142212-86-9)
- (S)-1-((R)-1-cyclohexyl-2-(methylamino)-2-oxoethyl)pyrrolidine-2-carboxylic acid (CAS 1421051-44-6)
- Sofosbuvir Impurity 61 (CAS 1496551-72-4)
- Ethyl 1-(4-chlorophenyl)-4-cyano-1H-pyrazole-5-carboxylate (CAS 956964-67-3)
- Anti-Inflammatory Peptide 1 (CAS 118850-71-8)
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