Everolimus Impurity 22 CAS CATO-C4X-112222
| CAS No. | CATO-C4X-112222 |
| Molecular Formula | C52H79NO13 |
| Molecular Weight | 926.18 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Everolimus Impurity 22.
CATO supplies Everolimus Impurity 22 (CAS CATO-C4X-112222), a pharmacopoeial impurity reference standard (molecular formula C52H79NO13, MW 926.18 g/mol) used for the identification and quantification of trace impurities in APIs.
Structurally, Everolimus Impurity 22 (C52H79NO13) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage. The molecule exhibits a degree of unsaturation (DBE) of 14.0, corresponding to approximately 14 ring(s) or double-bond equivalent(s). With a molecular weight of 926.18 g/mol, it falls into the high-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C52H79NO13 |
| Molecular Weight | 926.18 g/mol |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 14.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 1 |
Related Everolimus Standards
- Everolimus EP Impurity A-d3 (CAS 392711-19-2)
- Everolimus Impurity 15（Z&Emixture） (CAS 147438-27-5 (E-Isomer）)
- Everolimus Impurity 16 (CAS 147438-29-7)
- Everolimus Impurity 17 (CAS 253431-35-5)
- Everolimus EP Impurity A (CAS 53123-88-9)
- Everolimus EP Impurity E (CAS 1237826-25-3)
- Everolimus Impurity 49 (CAS CATO-C4X-112249)
- Everolimus Impurity 1 (CAS 745779-75-3)
Recommended Standards
- Cholyl-L-lysyl fluorescein (CAS 140616-46-2)
- 1-Piperidinyloxy, 4-[[(7R,18Z)-4-hydroxy-4-oxido-10-oxo-7-[[(9Z)-1-oxo-9-octadecen-1-yl]oxy]-3,5,9-trioxa-4-phosphaheptacos-18-en-1-yl]dimethylammonio]-2,2,6,6-tetramethyl-, inner salt (CAS 150480-57-2)
- Pivampicillin EP Impurity C (CAS CATO-C4X-23223)
- Bis(4-(3,3,4,4,5,5,5-heptafluoro-2,2-bis(trifluoromethyl)pentyl)phenyl)(phenyl)phosphine (CAS 322647-83-6)
- Eltrombopag Impurity 101 (CAS 2750368-89-7)
- Rosuvastatin Impurity 253 (CAS 958358-67-3)
- Bedaquiline Impurity 30 (CAS 654654-93-0)
- C-(3,5-Dimethyl-1H-pyrazol-4-yl)-C-phenyl-methylamine hydrochloride (CAS 1257848-41-1)
- 2-Chloro-5-(3-methyl-1H-indazol-5-yl)-1,3,4-thiadiazole (CAS 1188266-01-4)
- Tert-butyl (R)-4-(2-amino-3-methoxy-3-oxopropyl)-1H-pyrazole-1-carboxylate (CAS 2387561-50-2)
- 2-((5-(4-Chlorophenyl)-1,3,4-oxadiazol-2-yl)thio)-1-(indolin-1-yl)ethan-1-one (CAS 484695-40-1)
- 2,3,4-Tribromodibenzo[b,d]furan (CAS 617707-50-3)
- Ethyl 2-bromo-3-oxohexanoate (CAS 81569-68-8)
- Semaglutide impurity 34 (CAS CATO-C4X-222634)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com