Everolimus Impurity 49 CAS CATO-C4X-112249
| CAS No. | CATO-C4X-112249 |
| Molecular Formula | C52H79NO14 |
| Molecular Weight | 942.18 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Structurally, Everolimus Impurity 49 (C52H79NO14) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage. The molecule exhibits a degree of unsaturation (DBE) of 14.0, corresponding to approximately 14 ring(s) or double-bond equivalent(s). With a molecular weight of 942.18 g/mol, it falls into the high-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
CATO supplies Everolimus Impurity 49 (CAS CATO-C4X-112249), a pharmacopoeial impurity reference standard (molecular formula C52H79NO14, MW 942.18 g/mol) used for the identification and quantification of trace impurities in APIs.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C52H79NO14 |
| Molecular Weight | 942.18 g/mol |
| Purity | ≥95% |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 14.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 1 |
Related Everolimus Standards
- Everolimus EP Impurity E (CAS 1237826-25-3)
- Everolimus Impurity 1 (CAS 745779-75-3)
- Everolimus Impurity 13 (CAS CATO-C4X-112213)
- Everolimus EP Impurity C (CAS CATO-C4X-112231)
- Everolimus Impurity 30 (CAS CATO-C4X-112230)
- Everolimus Impurity 22 (CAS CATO-C4X-112222)
- Everolimus EP Impurity B (CAS 1062122-63-7)
- Everolimus Ring-Opening Impurity (Mixture of Isomers) (CAS 1708118-13-1)
Recommended Standards
- 1,2-Bis[bis(3,5-ditrifluoromethylphenyl)phosphino]ethane (CAS 199342-62-6)
- DMT-2′O-TC-rU Phosphoramidite (CAS 1219089-92-5)
- 1-(2,4,6-Trichlorophenyl)-3-(5-[a-(3-tert-butyl-4-hydroxyphenoxy)-N-tetradecanamido]-2-chloroanilino)-4-[3,4-dimethyloxyphenyl]azo-5-pyrazolone (CAS 65293-90-5)
- Amphotericin Impurity 9 (CAS CATO-C4X-18449)
- Sitafloxacin impurity 55 (CAS CATO-C4X-115555)
- Ornidazole Impurity 13 (CAS 742020-47-9)
- Azlocillin Impurity 8 (CAS CATO-C4X-23208)
- Methyl 1-(6-chloropyrimidin-4-yl)-1H-pyrazole-3-carboxylate (CAS 1232776-83-8)
- Brexpiprazole Impurity 147 (CAS CATO-C4X-1131147)
- 1'-Oxo-2'-phenyl-1',4'-dihydro-2'h-spiro[cyclohexane-1,3'-isoquinoline]-4'-carboxylic acid (CAS 60734-37-4)
- 4-Benzyl-5-(thiophen-2-yl)-4H-1,2,4-triazole-3-thiol (CAS 139614-67-8)
- 6-Chloro-1-methyl-2-(methylthio)pyrimidin-4(1H)-one (CAS 6943-36-8)
- 3-Amino-5-(2-chlorophenyl)pyrazole (CAS 126520-01-2)
- Insulin Glargine Metabolite M2 (CAS CATO-CPTD788867)
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