Everolimus Impurity 17 CAS 253431-35-5
| CAS No. | 253431-35-5 |
| Molecular Formula | C51H79NO13 |
| Molecular Weight | 914.17 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a process- or degradation-related impurity, Everolimus Impurity 17 (CAS 253431-35-5, C51H79NO13) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, Everolimus Impurity 17 is typically pale yellow to yellow amorphous powder. Its solid-state physicochemical attributes — including a molecular weight of 914.17 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Everolimus Impurity 17 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C51H79NO13 |
| Molecular Weight | 914.17 g/mol |
| Purity | >80% |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Nitrogen Atoms | 1 |
Related Everolimus Standards
- Everolimus Impurity 15（Z&Emixture） (CAS 147438-27-5 (E-Isomer）)
- Everolimus Impurity 16 (CAS 147438-29-7)
- Everolimus EP Impurity A (CAS 53123-88-9)
- Everolimus EP Impurity A-d3 (CAS 392711-19-2)
- Everolimus Impurity 22 (CAS CATO-C4X-112222)
- Everolimus Impurity 18 (CAS 141392-23-6)
- Everolimus EP Impurity E (CAS 1237826-25-3)
- Everolimus Impurity 49 (CAS CATO-C4X-112249)
Recommended Standards
- Rapamycin Impurity 12 (CAS 150821-39-9)
- Perfluorooctadecanoic Acid (CAS 16517-11-6)
- Rapamycin Impurity 19 (CAS 144293-63-0)
- Eprinomectin (CAS 123997-26-2)
- Labetalol Impurity 51 (CAS CATO-C4X-246651)
- Nintedanib Impurity 67 (CAS 40872-87-5)
- Drospirenone EP Impurity G (CAS 932388-90-4)
- Oxcarbazepine Impurity 34 (CAS CATO-C4X-116434)
- (S)-2-(tert-Butyl)piperazine (CAS 502482-37-3)
- Iohexol EP Impurity H (CAS CATO-CP120264)
- (5,5-Difluoro-5,6-dihydro-4H-pyrrolo[1,2-b]pyrazol-2-yl)methanol (CAS 2705870-89-7)
- O-2093 (CAS 439080-01-0)
- 4-((5-(Trifluoromethyl)pyridin-2-yl)oxy)aniline (CAS 71422-81-6)
- Acetyl tetrapeptide-3 (CAS 827306-88-7)
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