Fosaprepitant Impurity 14 CAS CATO-C4X-116814
| CAS No. | CATO-C4X-116814 |
| Molecular Formula | C23H22F7N4O8P |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 841.62 g/mol gives Fosaprepitant Impurity 14 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
Fosaprepitant Impurity 14 (CAS CATO-C4X-116814) is a certified pharmaceutical impurity reference standard with the molecular formula C23H22F7N4O8PC7H17NO5 and a molecular weight of 841.62 g/mol.
The molecular framework of Fosaprepitant Impurity 14 (C23H22F7N4O8PC7H17NO5) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a phosphate ester group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C23H22F7N4O8P C7H17NO5 |
| Molecular Weight | 841.62 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.5 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | F-containing |
| Nitrogen Atoms | 5 |
Related Fosaprepitant Standards
- Fosaprepitant impurity 55（R,S,R） (CAS 1185503-00-7(free base))
- Fosaprepitant Impurity 53 (CAS 1254261-32-9)
- Fosaprepitant Impurity 4 Dimeglumine (CAS 1523569-87-0)
- Fosaprepitant Impurity 19 (CAS 1623-07-0)
- Fosaprepitant Impurity 48 (CAS 1707-92-2)
- Fosaprepitant Impurity 6 (CAS 172822-01-4（free base）)
- Fosaprepitant Impurity 12 (CAS 2035475-10-4)
- Fosaprepitant Impurity 41 HCl (CAS 2377328-02-2)
Recommended Standards
- Ilaprazole Impurity 123 (CAS CATO-C4X-1130123)
- Cholecalciferol impurity 16 (CAS 86307-40-6)
- Ticagrelor Impurity 10 (CAS 1402150-32-6)
- 3-Bromo-2,5-dimethylpyridine 1-oxide (CAS 17117-20-3)
- 1-(Furan-2-yl)-n2-isopropyl-n1,n1-dimethylethane-1,2-diamine (CAS 1038256-10-8)
- Ac-Phg(4-OH)-OEt (CAS 1998216-23-1)
- rac 2-Stearoyl-3-chloropropanediol, 95% (CAS 1329611-08-6)
- 2-(Difluoromethyl)-4-methoxy-5-nitro-3-(trifluoromethyl)pyridine (CAS 1805068-18-1)
- 4-(4-Nitrophenoxy)phenol (CAS 22479-78-3)
- Insulin Degludec Impurity 1 (CAS 843666-26-2)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com