Fosaprepitant Impurity 45 CAS CATO-C4X-116845
| CAS No. | CATO-C4X-116845 |
| Molecular Formula | C23H23F7N4O9P2 |
| Molecular Weight | 694.39 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Fosaprepitant Impurity 45.
Fosaprepitant Impurity 45 (CAS CATO-C4X-116845) is a certified pharmaceutical impurity reference standard with the molecular formula C23H23F7N4O9P2 and a molecular weight of 694.39 g/mol.
Based on its molecular formula C23H23F7N4O9P2, Fosaprepitant Impurity 45 contains a flavonoid core, an amide group, a phosphate ester group, a hydroxyl group, an ether linkage, fluorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 694.39 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Fosaprepitant Impurity 45 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C23H23F7N4O9P2 |
| Molecular Weight | 694.39 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | F-containing |
| Nitrogen Atoms | 4 |
Related Fosaprepitant Standards
- Fosaprepitant Impurity 44 (CAS CATO-C4X-116844)
- Fosaprepitant Impurity 42 (CAS CATO-C4X-116842)
- Fosaprepitant Impurity 12 (CAS 2035475-10-4)
- Fosaprepitant Impurity 22 (CAS CATO-C4X-116822)
- Fosaprepitant Impurity 34 (CAS CATO-C4X-116834)
- Fosaprepitant Impurity 52 (CAS CATO-C4X-116852)
- Fosaprepitant impurity 10 (CAS CATO-C4X-116810)
- Fosaprepitant Impurity 35 (CAS CATO-C4X-116835)
Recommended Standards
- Florfenicol Impurity 12 (CAS CATO-C4X-207512)
- Anagrelide Impurity 16 (CAS CATO-C4X-224016)
- Florfenicol Impurity 5 (CAS CATO-C4X-20755)
- Avatrombopag Impurity 73 (CAS CATO-C4X-223473)
- Isoflurane EP Impurity D (CAS 32778-07-7)
- Trazodone Impurity 91 (CAS 53818-10-3 (free base))
- Vilanterol Impurity 10 HCl (CAS 2514696-13-8（free base）)
- Lumefantrine (CAS 82186-77-4)
- N-(4-bromophenyl)-2-chloronicotinamide (CAS 56149-25-8)
- 1-(3-Methylbenzyl)-1H-indole-3-carbonitrile (CAS 1226100-61-3)
- 4-Amino-5-chloronicotinamide (CAS 1823917-45-8)
- 3-Methyl-[2,3'-bipyridine]-5'-carboxylic acid (CAS 1346686-58-5)
- 2-(5-(Benzyloxy)-3-chloro-2-(trifluoromethyl)phenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (CAS 2883770-71-4)
- Osteoblast-Adhesive Peptide (CAS 193613-75-1)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com