Triamcinolone Acetonide Impurity 8 (Pretriamcinolone) CAS CATO-C4X-13268

Purity 97%+In StockPharmacopoeial Impurity Standards
CAS No.CATO-C4X-13268
Molecular FormulaC21H29FO5
Molecular Weight380.45 g/mol
CategoryPharmacopoeial Impurity Standards / EP Impurities
AvailabilityIn Stock

Chemical Structure

Triamcinolone Acetonide Impurity 8 (Pretriamcinolone) CAS CATO-C4X-13268 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 380.45 g/mol gives Triamcinolone Acetonide Impurity 8 (Pretriamcinolone) distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

As a process- or degradation-related impurity, Triamcinolone Acetonide Impurity 8 (Pretriamcinolone) (CAS CATO-C4X-13268, C21H29FO5) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.

Owing to a flavonoid core, a hydroxyl group, an ether linkage, fluorine substitution, Triamcinolone Acetonide Impurity 8 (Pretriamcinolone) is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 380.45 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.

This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.

CATO manufactures Triamcinolone Acetonide Impurity 8 (Pretriamcinolone) under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.

Physical & Chemical Properties

Molecular FormulaC21H29FO5
Molecular Weight380.45 g/mol
AppearanceOff-white to pale yellow crystalline powder. (slight halide-like odor)
Purity97%+
StorageStore at 2-8°C, protect from light, keep sealed and dry
Solubility (reference)Soluble in methanol, acetonitrile, DMSO, water (slightly soluble)
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)7.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
Halogen ContentF-containing

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