Domperidone Impurity 35 CAS CATO-C4X-142035
| CAS No. | CATO-C4X-142035 |
| Molecular Formula | C12H15ClN2O |
| Molecular Weight | 238.71 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a process- or degradation-related impurity, Domperidone Impurity 35 (CAS CATO-C4X-142035, C12H15ClN2O) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
The molecular framework of Domperidone Impurity 35 (C12H15ClN2O) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
As a certified reference material (CRM), Domperidone Impurity 35 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C12H15ClN2O |
| Molecular Weight | 238.71 g/mol |
| Purity | ≥95% |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Domperidone Standards
- Domperidone Impurity 14 (CAS 62780-84-1)
- Domperidone Impurity 30 (CAS 62780-76-1)
- Domperidone EP Impurity A (CAS 53786-28-0)
- Domperidone Impurity 18 (CAS 103784-04-9)
- Domperidone Impurity 4 (CAS 79923-70-9)
- Domperidone Impurity 13 (CAS 87120-77-2)
- Domperidone Impurity 23 (CAS 62780-89-6)
- Domperidone Impurity 15 (CAS 13733-33-0)
Recommended Standards
- Rosuvastatin Impurity 187 (CAS 154026-93-4)
- Atovaquone Related Compound 3 (CAS 1346600-43-8)
- Rosuvastatin Impurity 169 (CAS 404958-69-6)
- Glycerol Impurity 32 (CAS CATO-C4X-217132)
- Landiolol Impurity 69 (CAS CATO-C4X-262169)
- Risperidone Impurity 19 (CAS 84162-82-3)
- Phenobarbital Impurity 01 (CAS 69125-70-8)
- 3-Methyl-1-(4-methylquinolin-2-yl)-1,4-dihydroindeno[1,2-c]pyrazole (CAS 130946-61-1)
- 2-(Trifluoromethyl)pyridine 1-oxide (CAS 22253-71-0)
- 2-Methoxybenzo[d]thiazole-6-carbaldehyde (CAS 1368353-79-0)
- {1-azabicyclo[3.3.1]nonan-5-yl}methanol (CAS 148672-76-8)
- Diethyl sebacate (CAS 110-40-7)
- 3-Chloro-2-ethoxy-4H-pyrido[1,2-a]pyrimidin-4-one (CAS 88405-07-6)
- Crustacean Cardioactive Peptide (CAS 107090-96-0)
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