Loratadine Impurity 100 CAS CATO-C4X-1426100
| CAS No. | CATO-C4X-1426100 |
| Molecular Formula | C26H36ClN3O |
| Molecular Weight | 442.04 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Loratadine Impurity 100 (CAS CATO-C4X-1426100) is a certified pharmaceutical impurity reference standard with the molecular formula C26H36ClN3O and a molecular weight of 442.04 g/mol.
Loratadine Impurity 100 (C26H36ClN3O) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
As a certified reference material (CRM), Loratadine Impurity 100 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C26H36ClN3O |
| Molecular Weight | 442.04 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | ≥95% |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
Related Loratadine Standards
- Loratadine Impurity 41 (CAS CATO-C4X-142641)
- Loratadine Impurity 43 (CAS CATO-C4X-142643)
- Loratadine Impurity 53 (CAS CATO-C4X-142653)
- Loratadine Impurity 55 (CAS CATO-C4X-142655)
- Loratadine Impurity 81 (CAS CATO-C4X-142681)
- Loratadine Impurity 25 (CAS CATO-C4X-142625)
- Loratadine Impurity 47 (CAS CATO-C4X-142647)
- Loratadine Impurity 45 (CAS CATO-C4X-142645)
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