Betamethasone Impurity 119 CAS CATO-C4X-1437119
| CAS No. | CATO-C4X-1437119 |
| Molecular Formula | C44H57F2O12P |
| Molecular Weight | 846.89 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a process- or degradation-related impurity, Betamethasone Impurity 119 (CAS CATO-C4X-1437119, C44H57F2O12P) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Owing to a phosphate ester group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, a polycyclic aromatic system, Betamethasone Impurity 119 is typically pale yellow to yellow amorphous powder. Its solid-state physicochemical attributes — including a molecular weight of 846.89 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C44H57F2O12P |
| Molecular Weight | 846.89 g/mol |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 15.5 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | F-containing |
Related Betamethasone Standards
- Betamethasone Impurity 142 (CAS CATO-C4X-1437142)
- Betamethasone impurity 69 (CAS CATO-C4X-143769)
- Betamethasone Impurity 118 (CAS CATO-C4X-1437118)
- Betamethasone impurity 46 (CAS 2409521-73-7)
- Betamethasone Dipropionate impurity 02 (CAS 1186048-34-9)
- Betamethasone Dipropionate EP Impurity H (CAS 2575516-37-7)
- Betamethasone β-D-Glucuronide (CAS 744161-79-3)
- Betamethasone Dipropionate EP Impurity G (CAS 1186048-33-8)
Recommended Standards
- Dexamethasone Phosphate Diester (CAS CATO-C4X-116556)
- 4,4',4'',4'''-(Porphyrin-5,10,15,20-tetrayl)tetra(benzohydrazide) (CAS 323208-61-3)
- Phallacidin (CAS 26645-35-2)
- 5,10,15,20-Tetrakis[4-(methoxycarbonyl)phenyl]porphyrin (CAS 22112-83-0)
- Pioglitazone impurity 35 (CAS CATO-C4X-138335)
- Benserazide Impurity 26 (CAS CATO-C4X-142726)
- Nebivolol Impurity 93 (CAS CATO-C4X-196893)
- 1-(2-Methoxyethyl)-4-methylpiperazine (CAS 849459-55-8)
- (3R,4S)-1-((benzyloxy)carbonyl)-4-hydroxypyrrolidine-3-carboxylic acid (CAS 949495-18-5)
- Citalopram Impurity 72 (CAS 62498-69-5)
- (S)-1-(4-(1h-Pyrazol-1-yl)phenyl)ethan-1-ol (CAS 1344918-44-0)
- 1-Difluoromethoxy-4-nitro-3-(trifluoromethoxy)benzene (CAS 1807191-19-0)
- 2-(2-Aminoethyl)-1H-1,3-benzodiazole-5-carboxylic acid (CAS 902153-10-0)
- Semaglutide impurity 196 (CAS CATO-C4X-2226196)
Why CATO?
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