Itraconazole Impurity 62 CAS CATO-C4X-149762
| CAS No. | CATO-C4X-149762 |
| Molecular Formula | C35H37Cl2N7O4 |
| Molecular Weight | 690.62 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Itraconazole Impurity 62.
As a process- or degradation-related impurity, Itraconazole Impurity 62 (CAS CATO-C4X-149762, C35H37Cl2N7O4) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Itraconazole Impurity 62 (C35H37Cl2N7O4) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Itraconazole Impurity 62 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C35H37Cl2N7O4 |
| Molecular Weight | 690.62 g/mol |
| Purity | >95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 20.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 7 |
Related Itraconazole Standards
- Itraconazole Impurity 68 (CAS CATO-C4X-149768)
- Itraconazole Impurity 88 (CAS CATO-C4X-149788)
- Itraconazole EP Impurity G (CAS CATO-C4X-149789)
- Itraconazole Impurity 92 (CAS CATO-C4X-149792)
- Itraconazole Impurity 59 (CAS CATO-C4X-149759)
- Itraconazole Impurity 63 (CAS CATO-C4X-149763)
- Itraconazole Impurity 74 (CAS CATO-C4X-149774)
- Itraconazole Impurity 56 (CAS CATO-C4X-149756)
Recommended Standards
- Axitinib Impurity 57 (CAS CATO-C4X-107157)
- 4,4',4'',4'''-((9,9-Dimethyl-9H-xanthene-4,5-diyl)bis(phosphanetriyl))tetrabenzaldehyde (CAS 2411643-30-4)
- Adenosine, [P(R)]-5′-O-[(R)-hydroxymercaptophosphinyl]-P-thioadenylyl-(2′→5′)-, cyclic nucleotide (CAS 1638241-89-0)
- 4,4',4'',4'''-(1,4-Phenylenebis(1H-imidazole-2,4,5-triyl))tetrabenzoic acid (CAS 2594424-69-6)
- Palbociclib Impurity 205 (CAS 2252258-81-2)
- Atorvastatin Impurity 141 Calcium Salt (CAS 1046378-58-8)
- Hydrochlorothiazide Impurity 18 (CAS 89813-56-9)
- 7-Methyl-5,6,7,8-tetrahydrobenzo[4,5]thieno[2,3-d][1,2,3]triazin-4-ol (CAS 496038-39-2)
- 6-(5-(BOC-AMINO)-2-METHYLPHENYLAMINO)-3-METHYL-4-OXO-3,4-DIHYDROQUINAZOLINE (CAS 878745-39-2)
- 8-Ethyl-4-(4-fluorobenzoyl)-1-oxa-4,8-diazaspiro[4.5]decane-3-carboxylic acid (CAS 1326808-41-6)
- 5-Chloro-N-((1-ethylpyrrolidin-2-yl)methyl)-2-methoxybenzamide (CAS 92992-37-5)
- 1,5-Dibromo-3-(difluoromethyl)-2-fluorobenzene (CAS 1803776-87-5)
- N-(2,4-Dimethylphenyl)-2-oxo-1-{[3-(trifluoromethyl)phenyl]methyl}-1,2-dihydropyridine-3-carboxamide (CAS 339027-91-7)
- Semaglutide impurity 202 (CAS CATO-C4X-2226202)
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