Itraconazole Impurity 68 CAS CATO-C4X-149768
| CAS No. | CATO-C4X-149768 |
| Molecular Formula | C34H36Cl2N8O4 |
| Molecular Weight | 691.61 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Itraconazole Impurity 68.
Itraconazole Impurity 68 (CAS CATO-C4X-149768) is a certified pharmaceutical impurity reference standard with the molecular formula C34H36Cl2N8O4 and a molecular weight of 691.61 g/mol.
Itraconazole Impurity 68 (C34H36Cl2N8O4) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Itraconazole Impurity 68 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C34H36Cl2N8O4 |
| Molecular Weight | 691.61 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 20.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 8 |
Related Itraconazole Standards
- Itraconazole Impurity 88 (CAS CATO-C4X-149788)
- Itraconazole EP Impurity G (CAS CATO-C4X-149789)
- Itraconazole Impurity 62 (CAS CATO-C4X-149762)
- Itraconazole Impurity 92 (CAS CATO-C4X-149792)
- Itraconazole Impurity 59 (CAS CATO-C4X-149759)
- Itraconazole Impurity 63 (CAS CATO-C4X-149763)
- Itraconazole Impurity 74 (CAS CATO-C4X-149774)
- Itraconazole Impurity 56 (CAS CATO-C4X-149756)
Recommended Standards
- CAS 2172677-17-5 (CAS 2172677-17-5)
- N-[(11bS)-2,6-Bis(4-methoxyphenyl)-4-oxidodinaphtho[2,1-d:1′,2′-f][1,3,2]dioxaphosphepin-4-yl]-1,1,1-trifluoromethanesulfonamide (CAS 2757287-59-3)
- FIIN-3 (CAS 1637735-84-2)
- 3-([1,4'-Bipiperidin]-1'-ylmethyl)-7-bromo-N-(1-phenylcyclopropyl)-2-(3-(trifluoromethyl)phenyl)quinoline-4-carboxamide (CAS 1336960-13-4)
- Rivaroxaban Impurity 187 (CAS CATO-C4X-1090187)
- Almotriptan Impurity 13 (CAS CATO-C4X-153813)
- Arotinolol Impurity 54 (CAS CATO-C4X-185454)
- 2,5-Di(1-naphthyl)-1,3,4-oxadiazole (CAS 905-62-4)
- 3-Hydroxy-2,2-dimethylhexyl butyrate (CAS 85508-25-4)
- (4S,4'S)-1,1'-Bis(4-(tert-butyl)phenyl)-4,4'-diisopropyl-4,4',5,5'-tetrahydro-1H,1'H-2,2'-biimidazole (CAS 2641594-78-5)
- Landiolol Impurity 1 (CAS 144256-11-1)
- Furan, 3-chloro-2-ethynyltetrahydro-, (2R,3R)-rel- (CAS 122305-58-2)
- 6-Methyl-3H-[1,2,3]triazolo[4,5-b]pyridine (CAS 27582-21-4)
- Peptide 442 (CAS CATO-CPTD788442)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com