Itraconazole EP Impurity G(Mixture of Enantiomers) CAS CATO-C4X-14977
| CAS No. | CATO-C4X-14977 |
| Molecular Formula | 2*C44H41Cl4N11O6 |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies Itraconazole EP Impurity G(Mixture of Enantiomers) (CAS CATO-C4X-14977), a pharmacopoeial impurity reference standard (molecular formula C44H41Cl4N11O6, MW 961.68 g/mol) used for the identification and quantification of trace impurities in APIs.
Itraconazole EP Impurity G(Mixture of Enantiomers) (C44H41Cl4N11O6) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Itraconazole EP Impurity G(Mixture of Enantiomers) meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | 2*C44H41Cl4N11O6 |
| Molecular Weight | 961.68 g/mol |
| Purity | >95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 28.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 11 |
Related Itraconazole Standards
- Itraconazole Impurity 44 (CAS 103661-14-9)
- Itraconazole Impurity 41 (CAS 106461-41-0)
- Itraconazole Impurity 93 (CAS 110762-98-6)
- Itraconazole 2-Oxo Metabolite (CAS 112560-33-5)
- Itraconazole Impurity 38 (CAS 115897-54-6)
- Itraconazole N-Formyl-Ethlene Impurity (CAS 1199350-00-9)
- Itraconazole Impurity 73 (CAS 1199350-02-1)
- Itraconazole-d5(major) (CAS 1217510-38-7)
Recommended Standards
- Hydrocortisone Impurity 33 (CAS 77106-62-8)
- Gemcitabine Impurity 32 (CAS 122111-01-7)
- Aprepitant Impurity 13 (CAS 183664-56-4)
- 3-(Hydroxymethylene)-5-methoxyindolin-2-one (CAS 1018549-00-2)
- Ethyl 2-amino-2-(tetrahydro-2H-pyran-4-yl)acetate (CAS 646055-93-8)
- 3-Bromo-5-isopropylaniline (CAS 112930-36-6)
- 5-Hydroxy-3-(pent-4-en-1-yl)pyrazin-2(1H)-one (CAS 187997-07-5)
- 1-(5-Bromo-2-chlorophenyl)-2-methylpropan-1-amine (CAS 1270471-62-9)
- 4-(3-(Benzo[d][1,3]dioxol-5-yl)-1H-pyrazol-5-yl)-1-(phenylsulfonyl)piperidine (CAS 1025724-86-0)
- Fibrinopeptide A (human) (CAS 25422-31-5)
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