Camptothecin impurity 19 CAS CATO-C4X-157119
| CAS No. | CATO-C4X-157119 |
| Molecular Formula | C22H26N2O4 |
| Molecular Weight | 382.45 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a process- or degradation-related impurity, Camptothecin impurity 19 (CAS CATO-C4X-157119, C22H26N2O4) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
The molecular framework of Camptothecin impurity 19 (C22H26N2O4) is characterized by a flavonoid core, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
CATO manufactures Camptothecin impurity 19 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C22H26N2O4 |
| Molecular Weight | 382.45 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 2 |
Related Camptothecin Standards
- Camptothecin Impurity 12 (CAS 19685-10-0)
- 11-Ethyl Camptothecin (CAS 185807-29-8)
- Camptothecin Impurity 13 (CAS 91421-42-0)
- Camptothecin Impurity 11 (CAS 2569708-76-3)
- Camptothecin Impurity 10 (CAS 68426-53-9)
- Camptothecin impurity 17 (CAS 86639-48-7)
- Camptothecin Impurity 9 (CAS 67656-30-8)
- 7-Methyl Camptothecin (CAS 78287-26-0)
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Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com