Irinotecan EP Impurity H HCl CAS CATO-C4X-15714
| CAS No. | CATO-C4X-15714 |
| Molecular Formula | C32H36N4O6 |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 609.12 g/mol gives Irinotecan EP Impurity H HCl distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
As a process- or degradation-related impurity, Irinotecan EP Impurity H HCl (CAS CATO-C4X-15714, C32H36N4O6HCl) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution, Irinotecan EP Impurity H HCl is typically pale yellow to yellow amorphous powder. Its solid-state physicochemical attributes — including a molecular weight of 609.12 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C32H36N4O6 HCl |
| Molecular Weight | 609.12 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 16.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 4 |
Related Irinotecan Standards
- Irinotecan Hydrochloride (CAS 100286-90-6)
- Irinotecan Impurity 70 (CAS 100286-91-7)
- Irinotecan Impurity 69 (CAS 100286-92-8)
- Irinotecan Impurity 72 (CAS 100286-93-9)
- Irinotecan Impurity 71 (CAS 100286-94-0)
- Irinotecan Impurity N1 (CAS 1026078-50-1)
- Irinotecan EP Impurity A (CAS 103816-16-6)
- Irinotecan Impurity 14 (CAS 110351-94-5)
Recommended Standards
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- 1-Methyl-4-(4-piperidinyl)-2(1H)-pyridinone dihydrochloride (CAS 2169998-43-8)
- 1-Bromo-2,4-difluoro-5-propoxybenzene (CAS 1881290-38-5)
- (S)-1-(4-Chloro-3-methylphenyl)ethanamine hydrochloride (CAS 1624272-56-5)
- 3,4-Dihydro-2H-benzo[b][1,4]oxazine-8-carbonitrile (CAS 115661-89-7)
- Nintedanib Impurity 185 (CAS 652140-07-3)
- 4-((2,3-Dihydro-1H-inden-5-yl)oxy)aniline (CAS 937607-41-5)
- D-Tyr1-Tirzepatide (CAS CATO-CPTD788928)
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