Dasatinib Impurity 33 CAS CATO-C4X-160733
| CAS No. | CATO-C4X-160733 |
| Molecular Formula | C28H39N9O3S |
| Molecular Weight | 581.73 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Dasatinib Impurity 33.
CATO supplies Dasatinib Impurity 33 (CAS CATO-C4X-160733), a pharmacopoeial impurity reference standard (molecular formula C28H39N9O3S, MW 581.73 g/mol) used for the identification and quantification of trace impurities in APIs.
Dasatinib Impurity 33 (C28H39N9O3S) contains a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C28H39N9O3S |
| Molecular Weight | 581.73 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 14.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 9 |
| Sulfur Atoms | 1 |
Related Dasatinib Standards
- Dasatinib Impurity 37 (CAS 2468737-87-1)
- Dasatinib Impurity 5 (CAS 1159977-13-5)
- Dasatinib Impurity 16 (CAS 2468737-80-4)
- Dasatinib Carboxylic Acid Ethyl Ester (CAS 910297-62-0)
- Dasatinib Impurity 6 (CAS CATO-C4X-16076)
- Dasatinib Impurity 64 (CAS 2468737-75-7)
- Dasatinib Impurity 65 (CAS 2468737-76-8)
- Dasatinib Impurity 66 (CAS 2468737-89-3)
Recommended Standards
- 2-(4-Ethyl-piperazin-1-yl)-N-[4-(2-morpholin-4-yl-4-oxo-1,4-dihydro-quinolin-8-yl)-dibenzothiophen-1-yl]-acetamide (CAS 912824-29-4)
- Des(isopropylthiazolyl) Ritonavir (CAS 176655-57-5)
- 2-Chloro-6-methylpyridine (CAS 18368-63-3)
- Pyridine-6-[4-[2-[5-ethyl-6-[4-[2-(5-ethyl-2-pyridinyl)ethoxy]phenyl] pioglitazone (CAS 669716-56-7)
- Clopidogrel Impurity 73 HCl (CAS CATO-C4X-102973)
- Neratinib Impurity N1 (CAS 848139-78-6)
- Bilastine impurity 91 (CAS 2245209-60-1)
- 1,2,6-Trimethylpiperidin-4-ol (CAS 90226-91-8)
- 1-(1H-Benzo[d]imidazol-2-yl)-N,N-dimethylmethanamine (CAS 108274-97-1)
- Meropenem Impurity 30 (CAS CATO-C4X-130930)
- (2-Oxo-1,3-benzoxazol-3(2H)-yl)acetaldehyde (CAS 13610-81-6)
- 1-Cyclohexyl-3-(2-(thiophene-2-carbonyl)-1,2,3,4-tetrahydroisoquinolin-7-yl)urea (CAS 1207023-67-3)
- Alogliptin Impurity 3 (CAS 1108731-49-2)
- Semaglutide Impurity 11 (CAS CATO-C4X-222611)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com