Efavirenz Impurity 24 CAS CATO-C4X-162724
| CAS No. | CATO-C4X-162724 |
| Molecular Formula | C14H9ClF3NO2 |
| Molecular Weight | 315.67 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO manufactures Efavirenz Impurity 24 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
As a process- or degradation-related impurity, Efavirenz Impurity 24 (CAS CATO-C4X-162724, C14H9ClF3NO2) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
The molecular framework of Efavirenz Impurity 24 (C14H9ClF3NO2) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | C14H9ClF3NO2 |
| Molecular Weight | 315.67 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 1 |
Related Efavirenz Standards
- Efavirenz (CAS 154598-52-4)
- Efavirenz Impurity 10 (CAS 2125704-30-3)
- Efavirenz Impurity 2 (CAS 154801-74-8)
- Efavirenz Impurity 25 (CAS CATO-C4X-162725)
- Efavirenz Impurity 28 (CAS CATO-C4X-162728)
- Efavirenz Racemate (CAS 177530-93-7)
- Efavirenz 2-Desoxo-2-methly (CAS 1258498-53-1)
- Efavirenz USP Related Compound B (CAS 440124-96-9)
Recommended Standards
- Sorafenib Impurity 4 (CAS 871555-75-8)
- 4-[3-Chloro-5-(trifluoromethyl)pyridin-2-yl]benzohydrazide (CAS 1092343-30-0)
- N-[2-Chloro-5-(trifluoromethyl)phenyl]-2-hydroxybenzamide (CAS 5683-92-1)
- 4-(4-Chloro-2-(trifluoromethyl)phenyl)-N-hydroxypicolinimidamide (CAS 1219454-39-3)
- Procaterol Impurity 37 (CAS CATO-C4X-181037)
- Amoxicillin Impurity 17 (CAS 1313237-94-3)
- Vardenafil Impurity 42 (CAS CATO-C4X-101742)
- tert-Butyl 4-(3-oxo-4-phenylbutanoyl)piperidine-1-carboxylate (CAS 301219-11-4)
- Cefoperazone EP Impurity C (Potassium salt) (CAS 62557-28-2)
- ethyl 6-(3-hydroxyprop-1-ynyl)-2H-chromene-3-carboxylate (CAS 2646915-00-4)
- 1-n-Methyl-1-n-phenylbenzene-1,2-diamine (CAS 50374-92-0)
- 5-Fluoro-2-(1h-1,2,4-triazol-1-yl)aniline (CAS 869942-02-9)
- N,N-Dimethyl-2-(2-oxo-2,3-dihydro-1H-imidazol-4-yl)acetamide (CAS 952733-80-1)
- Semaglutide impurity 108 (CAS CATO-C4X-2226108)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com