Efavirenz Impurity 10 CAS 2125704-30-3
| CAS No. | 2125704-30-3 |
| Molecular Formula | C14H9ClF3NO2 |
| Molecular Weight | 315.67 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Efavirenz Impurity 10.
Efavirenz Impurity 10 (CAS 2125704-30-3) is a certified pharmaceutical impurity reference standard with the molecular formula C14H9ClF3NO2 and a molecular weight of 315.67 g/mol.
Structurally, Efavirenz Impurity 10 (C14H9ClF3NO2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 9.0, corresponding to approximately 9 ring(s) or double-bond equivalent(s). With a molecular weight of 315.67 g/mol, it falls into the moderately-high-molecular-weight range. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO manufactures Efavirenz Impurity 10 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C14H9ClF3NO2 |
| Molecular Weight | 315.67 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1997 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 1 |
Related Efavirenz Standards
- Efavirenz (CAS 154598-52-4)
- Efavirenz Impurity 2 (CAS 154801-74-8)
- Efavirenz Impurity 24 (CAS CATO-C4X-162724)
- Efavirenz Impurity 25 (CAS CATO-C4X-162725)
- Efavirenz Impurity 28 (CAS CATO-C4X-162728)
- Efavirenz Racemate (CAS 177530-93-7)
- Efavirenz 2-Desoxo-2-methly (CAS 1258498-53-1)
- Efavirenz USP Related Compound B (CAS 440124-96-9)
Recommended Standards
- Sorafenib Impurity 4 (CAS 871555-75-8)
- N-[2-Chloro-5-(trifluoromethyl)phenyl]-2-hydroxybenzamide (CAS 5683-92-1)
- N-(4-chlorophenyl)-2,2-difluoro-2-(4-fluorophenoxy)acetamide (CAS 338792-33-9)
- Methyl 4-[3-chloro-5-(trifluoromethyl)-2-pyridinyl]benzenecarboxylate (CAS 885949-65-5)
- Tolvaptan Impurity 52 (CAS CATO-C4X-195552)
- Amorolfine impurity 73 (CAS 78613-39-5)
- Valsartan Impurity 109 (CAS 2407652-86-0)
- 4-(2-Bromo-4-isopropylphenoxy)piperidinehydrochloride (CAS 1220019-07-7)
- 2-Isopropyl-2H-indazole-3-carboxylic acid methyl ester (CAS 173600-07-2)
- 3-(Trifluoromethyl)anisole (CAS 454-90-0)
- 2-(8-Bromo-2,3-dihydrobenzo[b][1,4]dioxin-6-yl)acetic acid (CAS 1534732-17-6)
- Ethyl 2-((2-chloro-4-fluorophenyl)imino)-4-(trifluoromethyl)-2,3-dihydrothiazole-5-carboxylate (CAS 937597-86-9)
- 2-Amino-2-(3-chloropyridin-4-yl)ethanol hydrochloride (CAS 1956389-98-2)
- Pancreatic Polypeptide (1-17)-(Ala31,Aib32)-Neuropeptide Y (18-36) (human) trifluoroacetate salt (CAS 313988-70-4)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com